Intraductal papilloma. In: Lakhani SR, Ellis IO, Schnitt SJ, Tan PH, van de Vijver MJ, eds.
Most AMEs appear to represent variants of
intraductal papilloma. (3) The differentiation of papilloma with prominent myoepithelial cells from AMEs can be made based on architecture, pattern, and degree of myoepithelial proliferation.
(%) of Cases DCIS/LCIS 7 (1.4) DCIS/IP/RS 6 (1.2) DCIS/ADH 1 (0.2) DCIS/hamartoma 1 (0.2) DCIS alone 39 (7.7) Total 54 (10.7) Abbreviations: ADH, atypical ductal hyperplasia; IP,
intraductal papilloma; LCIS, lobular carcinoma in situ; RS, radial scar.
Intraductal papillomas are generally solitary and located in the subareolar region in the major and lactiferous ducts, hence the derivation of the term central/solitary papilloma.
The market for global
intraductal papilloma is constrained by the lack of awareness, high cost of surgery, complications of the surgery, lack of focus on women health in the developing and poorer regions of the world etc.
Excision is indicated for
intraductal papilloma of the breast diagnosed on core needle biopsy.
Histological examination of a core biopsy revealed
intraductal papilloma, and although follow-up was recommended unfortunately it was not performed.
Diagnosis of breast cancer with mammography is established on the difference of density of lesion and surrounding tissue.20 In this study, among the lesions in grade 4A, there were 13 cases of benign lesions including two cases of adenoma, five cases of adenoma fibrosum, two cases of
intraductal papilloma, one case of mastitis, one case of breast phyllodes tumor, one case of hyperplasia of mammary glands and one case of granulomatous inflammation and seven cases of malignant lesions.
In the present study, fibrocystic disease is the predominant benign lesion comprising 39 cases (41%), followed by fibroadenoma 26 cases (28%), fibrocystic disease with columnar cell change 13 cases (14%), sclerosing adenosis 8 cases (8%),
intraductal papilloma 5 cases (5%), apocrine adenoma 3 cases (3%), benign phyllodes 1 case (1%) (Figure 2).
Two cases of
intraductal papilloma were diagnosed on cytology.
Intraductal papilloma is a benign growth within the ductal system and presents as bloody nipple discharge.
Of these 7 patients, 2 underwent excisional biopsies, demonstrating an invasive lobular carcinoma in 1, and an
intraductal papilloma in the other.
