intraductal carcinoma

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in·tra·duc·tal car·ci·no·ma

a form of carcinoma derived from the epithelial lining of ducts, especially in the breast, where most carcinomas arise from ductal epithelium; the neoplastic cells proliferate in irregular papillary projections or masses, filling the lumens, that are solid, cribriform, or centrally necrotic; intraductal carcinoma is a form of carcinoma in situ because it is contained by the ductal basement membrane; when it invades surrounding stroma or metastasizes, it is referred to as ductal carcinoma.

intraductal carcinoma

Etymology: L, intra + ductus, duct
a neoplasm that occurs most often in the breast but can occur elsewhere, as in the salivary glands. The lesion on cross section usually shows well-differentiated tumor cells in calcified and dilated ducts.
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Intraductal carcinoma of the salivary gland

Patient discussion about intraductal carcinoma

Q. Hi all. I was diagnosed with DCIS in April. Had a lumpectomy about 3 cm and it was removed. Am I cured fully? Hi all. I was diagnosed with DCIS in April. Had a lumpectomy about 3 cm and it was removed. I then had 28 radiation and 4 boosters. I went to the cancer center for my checkup and the doctor said nothing to worry. They didn’t advice me further follow up and I am normal for the past 6 months and not even taking tamoxifen. I am quite normal like others. Am I cured fully?

A. Hey nothing to worry!! Early diagnosis is half cured. The same thing applies to your case. With early diagnosis and treatment, the doctors should have removed the cancer parts with the surgery. Based on the report they have given you radiation and other meds. If you be estrogen +ve then they would have given you it as a preventive. By the way if you have any doubts better approach your doctor and have your checkup done as a precautionary measure.

Q. My wife is diagnosed with DCIS type of breast cancer. My wife is diagnosed with DCIS type of breast cancer. Doctors had staged my wife`s cancer as low. She is still due for some tests which she will soon have. Doctor have told that there is nothing much to worry so why are they taking so many tests?

A. All the tests are taken to confirm about the type of treatment to be given. These pre treatment tests can avoid the risk of post treatment complications. Even if the complications arise they will know the best possible course of counter treatment. So please cooperate with the doctor.

More discussions about intraductal carcinoma
References in periodicals archive ?
Intraductal carcinoma of the prostate: precursor or aggressive phenotype of prostate cancer?
Historically, the term intraductal carcinoma of the prostate (IDCP) was used variably to describe prostatic acinar adenocarcinoma, prostatic ductal adenocarcinoma, and urothelial carcinoma showing extension into prostatic ducts and acini.
Contemporary literature often attributes the original description of intraductal carcinoma of the prostate (IDCP) to Kovi et al (51) (1985) and McNeal and Yemoto (19) (1996), who noted its association with higher-grade cancer and interpreted it as a secondary spread inside the ducts rather than a precursor lesion.
On one end of this spectrum, intraductal carcinoma of the prostate (IDC-P) is often associated with late-stage, high-grade invasive prostatic adenocarcinoma and requires either definitive therapy or immediate rebiopsy.
Solid papillary carcinoma of the breast: aform of intraductal carcinoma with endocrine differentiation frequently associated with mucinous carcinoma.
49,50) Because of overlapping features with high-grade prostatic intraepithelial neoplasia, strict criteria need to be applied to diagnose intraductal carcinoma.
Pathologic findings from the National Surgical Adjuvant Breast Project (NSABP) protocol B-17: intraductal carcinoma (ductal carcinoma in situ).
The article by Brian Robinson, MD, Cristina Magi Galluzzi, MD, PhD, and Ming Zhou, MD, PhD, deals with intraductal carcinoma of the prostate (IDC-P), that is, a proliferation of secretory cells within the prostate ducts and acini with marked architectural and cytologic atypia that is more pronounced than that found in high-grade prostatic intraductal neoplasia.
These atypical cribriform/solid lesions with basal cells represent either cribriform high-grade prostatic intraepithelial neoplasia (HGPIN) or intraductal carcinoma of the prostate (IDC-P).
Standard histologic criteria for in situ lobular carcinoma and intraductal carcinoma were used.
Microscopically, SDCs are characterized by both infiltrative and intraductal carcinoma resembling breast ductal carcinoma (Figure 3, A).
Most cases of cystic hypersecretory carcinoma are intraductal carcinomas with no invasive component.