intraductal carcinoma

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in·tra·duc·tal car·ci·no·ma

a form of carcinoma derived from the epithelial lining of ducts, especially in the breast, where most carcinomas arise from ductal epithelium; the neoplastic cells proliferate in irregular papillary projections or masses, filling the lumens, that are solid, cribriform, or centrally necrotic; intraductal carcinoma is a form of carcinoma in situ because it is contained by the ductal basement membrane; when it invades surrounding stroma or metastasizes, it is referred to as ductal carcinoma.

intraductal carcinoma

Etymology: L, intra + ductus, duct
a neoplasm that occurs most often in the breast but can occur elsewhere, as in the salivary glands. The lesion on cross section usually shows well-differentiated tumor cells in calcified and dilated ducts.
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Intraductal carcinoma of the salivary gland

Patient discussion about intraductal carcinoma

Q. Hi all. I was diagnosed with DCIS in April. Had a lumpectomy about 3 cm and it was removed. Am I cured fully? Hi all. I was diagnosed with DCIS in April. Had a lumpectomy about 3 cm and it was removed. I then had 28 radiation and 4 boosters. I went to the cancer center for my checkup and the doctor said nothing to worry. They didn’t advice me further follow up and I am normal for the past 6 months and not even taking tamoxifen. I am quite normal like others. Am I cured fully?

A. Hey nothing to worry!! Early diagnosis is half cured. The same thing applies to your case. With early diagnosis and treatment, the doctors should have removed the cancer parts with the surgery. Based on the report they have given you radiation and other meds. If you be estrogen +ve then they would have given you it as a preventive. By the way if you have any doubts better approach your doctor and have your checkup done as a precautionary measure.

Q. My wife is diagnosed with DCIS type of breast cancer. My wife is diagnosed with DCIS type of breast cancer. Doctors had staged my wife`s cancer as low. She is still due for some tests which she will soon have. Doctor have told that there is nothing much to worry so why are they taking so many tests?

A. All the tests are taken to confirm about the type of treatment to be given. These pre treatment tests can avoid the risk of post treatment complications. Even if the complications arise they will know the best possible course of counter treatment. So please cooperate with the doctor.

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References in periodicals archive ?
Patterns of differentiation and proliferation in intraductal carcinoma of the prostate: significance for cancer progression.
Distinction between intraductal carcinoma of the prostate (IDC-P), high-grade dysplasia (PIN), and invasive prostatic adenocarcinoma, using molecular markers of cancer progression.
ETS gene aberrations in atypical cribriform lesions of the prostate: implications for the distinction between intraductal carcinoma of the prostate and cribriform high-grade prostatic intraepithelial neoplasia.
Intraductal carcinoma of the prostate: a distinct histopathological entity with important prognostic implications.
Histologic Features That May Be Seen in Intraductal Carcinoma of the Prostate (IDC-P) IDC-P glands, No.
Intraductal carcinoma of the prostate should be differentiated from other prostate lesions with cribriform and/ or solid architecture, which range from normal histologic structures or benign lesions to premalignant lesions and frank malignancies (Table 3).
Intraductal carcinoma of the prostate stains positive for prostate-specific markers, including PSA, prostate-specific acid phosphatase, prostate-specific membrane antigen, and P501S, whereas stains for basal cells, such as CK5/6, 34[beta]E12, and p63, are positive only in the basal cells at the periphery of the cancer glands.
49,50) Because of overlapping features with high-grade prostatic intraepithelial neoplasia, strict criteria need to be applied to diagnose intraductal carcinoma.
Most cases of cystic hypersecretory carcinoma are intraductal carcinomas with no invasive component.