intraductal carcinoma

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in·tra·duc·tal car·ci·no·ma

a form of carcinoma derived from the epithelial lining of ducts, especially in the breast, where most carcinomas arise from ductal epithelium; the neoplastic cells proliferate in irregular papillary projections or masses, filling the lumens, that are solid, cribriform, or centrally necrotic; intraductal carcinoma is a form of carcinoma in situ because it is contained by the ductal basement membrane; when it invades surrounding stroma or metastasizes, it is referred to as ductal carcinoma.
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Patient discussion about intraductal carcinoma

Q. Hi all. I was diagnosed with DCIS in April. Had a lumpectomy about 3 cm and it was removed. Am I cured fully? Hi all. I was diagnosed with DCIS in April. Had a lumpectomy about 3 cm and it was removed. I then had 28 radiation and 4 boosters. I went to the cancer center for my checkup and the doctor said nothing to worry. They didn’t advice me further follow up and I am normal for the past 6 months and not even taking tamoxifen. I am quite normal like others. Am I cured fully?

A. Hey nothing to worry!! Early diagnosis is half cured. The same thing applies to your case. With early diagnosis and treatment, the doctors should have removed the cancer parts with the surgery. Based on the report they have given you radiation and other meds. If you be estrogen +ve then they would have given you it as a preventive. By the way if you have any doubts better approach your doctor and have your checkup done as a precautionary measure.

Q. My wife is diagnosed with DCIS type of breast cancer. My wife is diagnosed with DCIS type of breast cancer. Doctors had staged my wife`s cancer as low. She is still due for some tests which she will soon have. Doctor have told that there is nothing much to worry so why are they taking so many tests?

A. All the tests are taken to confirm about the type of treatment to be given. These pre treatment tests can avoid the risk of post treatment complications. Even if the complications arise they will know the best possible course of counter treatment. So please cooperate with the doctor.

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References in periodicals archive ?
Systematic review links the prevalence of intraductal carcinoma of the prostate to prostate cancer risk categories.
The examination of the much larger surgical specimen revealed that, although the bulk of the tumor represented high-grade osteosarcoma (99% of tumor volume), the presence of adjacent foci of infiltrating ductal carcinoma and highgrade intraductal carcinoma indicated that the tumor was much more likely to be a metaplastic ductal carcinoma with osteosarcomatous differentiation than a primary extraskeletal mammary osteosarcoma.
18.) The pure form of these tumors shows no signs of invasion, but in about 75% of cases, intraductal carcinoma also is found.[2] If the tumor exhibits any signs of invading adjacent tissue, it usually is classified as a nonpure form of mucinous breast cancer and is treated differently than pure mucinous breast cancer.
HGPIN should not be confused with intraductal carcinoma. The latter, even when isolated in a prostate biopsy, carries a predictive value of 100% for cancer in a repeat biopsy.
She underwent operation left breast excision with axillary dissection because of intraductal carcinoma (comedocarcinoma) and fibrocystic disease in 1996.
Histological types of MBC in our casuistry MBC cases Histologic type (number %) Invasive Ductal carcinoma (NST) 5(50) Invasive cribriform carcinoma 1(10) Mixed type invasive carcinoma 2(20) Cribriform intraductal carcinoma 1(10) Adenomyoepithelioma of the breast 1(10) Table 2.
Intraductal carcinoma of the prostate metastatic to the penile urethra: A rare demonstration of two morphologic patterns of tumor growth.
Study patients included 24 women with intraductal carcinoma, 15 women with mucinous carcinoma, 5 women with in situ lobular carcinoma, 2 women with medullary carcinoma, and 14 women with breast diseases but no evidence of cancer.
Conversely, common premalignant and malignant cribriform lesions include high-grade prostatic intraepithelial neoplasia (HGPIN) and the cribriform pattern of invasive acinar adenocarcinoma (Gleason pattern 4), respectively, and less common entities, though still clinically important, are ductal adenocarcinoma and intraductal carcinoma of the prostate (IDC-P).
Histological reports proved all (100%) to be intraductal carcinoma. Of the 13 patients, 9 (69%) patients were subjected to modified radical mastectomy, 6(46%) patients received adjuvant chemotherapy of the 6, 3(50%) received CEF, 2(33%) received CAF with Paclitaxel and 1(17%) received paclitaxel with trastuzumab, 3(23%) received adjuvant radiation and 8(62%) received adjuvant hormonal therapy with tamoxifen (Figure 4).
Intraductal carcinoma of the prostate is a very important malignant condition with cribriform pattern, given its association with worse prognosis requiring prompt definitive treatment.