intestinal transplantation

intestinal transplantation

Surgical insertion and connection of a donated length of small intestine as a treatment for short gut syndrome or other forms of intestinal failure or extensive intestinal tumour. The procedure is a radical alternative to intravenous feeding (total parenteral nutrition). In most cases the liver is transplanted along with the intestine. Currently, less than half the patients who have this major procedure survive for three years but the operation is still in its infancy and improved results are to be expected with time and experience.
References in periodicals archive ?
Patients (7/13) who were diagnosed with PIPO at our pediatric gastroenterology clinic and patients (6/13) who were referred for intestinal transplantation between February 2012 and February 2018 were included in the study.
Intestinal transplantation is the only long-term option for patients with Crohn's and other diseases if their intestines fail.
Segovia, "A case report of acute cellular rejection following intestinal transplantation managed with adalimumab," Transplantation Proceedings, vol.
Riyadh, Rabi'II 08, 1439, December 26, 2017, SPA -- After a successful 10-hour intestinal transplantation, a medical team at King Faisal Specialist Hospital and Research Centre in Riyadh put an end to the suffering of a saudi youth (20-year-old) who suffered from "short-bowel syndrome", which resulted in many health problems, including temporary blindness.
Keywords: Small bowel transplantation, intestinal transplantation, stem cell transplantation, small bowel insufiency, short bowel syndrome
Surviving patients frequently require long-term parenteral nutrition [1, 2, 12, 15] or eventual intestinal transplantation [1,2].
Currently, intestinal transplantation (ITx) is offered to patients with irreversible IF and total parenteral nutrition (TPN) failure in which survival on TPN is compromised [2, 5, 6].
With the increasing popularity and viability of intestinal transplantation, we hope that our case provides an impetus for the systematic collection of prospective data from postintestinal transplantation cohorts aimed at identifying reliable and preferably noninvasive biomarkers and predictors for rejection events.
Physicians from the US and Europe describe normal and abnormal physiology, presenting features, clinical and nutritional assessment, and outcomes, including metabolic problems, gallstones, and renal stones, as well as medical, nutritional, and surgical treatments, including intestinal transplantation. They also discuss the use of growth factors; drug delivery and bioavailability; psychosocial aspects of quality of life; and multidisciplinary teams.
In rat intestinal transplantation, HRUW can reduce graft damage and protect the recipient from the systemic effects of transplantation via alleviating graft oxidative stress, ultimately facilitating recipient survival [43].
Nowadays, the intestinal transplantation is only used for treating severe cases of small bowel syndrome.