intestinal metaplasia

Also found in: Acronyms.

in·tes·ti·nal met·a·pla·si·a

the transformation of mucosa, particularly in the stomach, into glandular mucosa resembling that of the intestines, although usually lacking villi.
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Specific topics to be discussed include the diagnostic criteria for Barrett esophagus and intestinal metaplasia, the importance of the gastric cardia, and potential pitfalls in the diagnosis of dysplasia among patients with Barrett esophagus.
The major goal is to develop markers that can predict which patients with intestinal metaplasia or lowgrade dysplasia will develop cancer" and which ones will not, although he noted that "we are far" from being able to do that.
This, therefore, implies that metaplastic, non-goblet cell-containing columnar epithelium in the distal esophagus does not impart a similar risk of adenocarcinoma and, as such, a diagnosis of BE should not be rendered in the absence of intestinal metaplasia (IM) (Figure 2).
Intestinal metaplasia of the esophagus is a premalignant lesion for adenocarcinoma of the esophagus, which is the cancer that has had the most rapid rise in incidence in the United States.
Pyloric gland adenomas were associated with autoimmune atrophic gastritis and intestinal metaplasia in the surrounding mucosa.
Of these 34 patients, 18 (53%) had at least two initial consecutive endoscopies that revealed intestinal metaplasia without dysplasia over a mean time period of 2 years.
Apart from mild to moderate autolysis of the mucosa, no pathologic mucosal conditions, such as H pylori infection, atrophy-related alterations, or intestinal metaplasia, could be identified.
Sijunzi decoction can be used to treat many diseases, such as chronic gastritis, intestinal metaplasia, gastric and duodenal ulcer (15).
There was no evidence of Helicobacter pylori-associated inflammation, activity, or intestinal metaplasia.
Conclusion: Permanent impairment in the conjugation of cell and tissue components in mucosa accompanied by the change of an epithelial layer synthetic function with the impaired physicochemical properties of gastric mucin results in intestinal metaplasia as early as in childhood.
7% of these patients ("slightly symptomatic" and asymptomatic) had gastric atrophy or intestinal metaplasia, therefore they are at high risk to develop severe complications.

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