interventional clinical trial

A clinical trial that intervenes with the inviolability (here, safety) of the trial subject for the purpose of the investigation, which may include administration of an investigational medical product to the subject or use of some extra means of intervention (i.e., sampling, testing or administration of a questionnaire) that would not otherwise be used.

References in periodicals archive ?

The first Cadrock interventional clinical trial of the triple therapy at Liverpool Hospital, Sydney Australia, has just enrolled its second patient.

Cadrock Secures US$5m for Therapy Targeting $35 billion Heart Disease Market

Results of an interventional clinical trial demonstrate that a spinal-cord stimulation system to restore cough can be used safely and effectively in conjunction with a diaphragm pacing system to restore breathing.

Restoring Respiratory Function

FDA has indicated that in order to conduct a human interventional clinical trial with a dietary supplement on a "diseased" population, an Investigational New Drug (IND) application must be filed.

Research at your own risk: navigating the complex world of dietary supplement research can be challenging for even the most seasoned professionals

An interventional clinical trial consists of any research study that prospectively assigns humans or groups of humans to health-related interventions (drugs, cells and biological products, devices, procedures, behavioral treatments, etc).

The rationale for a registry of clinical trials involving human stem cell therapies

The TIDES trial, Takedas largest interventional clinical trial to date, enrolled over 20,000 healthy children and adolescents ages four to 16 years living in dengue-endemic areas.

Japan : Takedas Dengue Vaccine Candidate Meets Primary Endpoint in Pivotal Phase 3 Efficacy Trial

Whether it is library-based, petri dish-based or even a human interventional clinical trial, it is the research and what is uncovered that helps drive innovation, new product creation, sales channels and much more.

Its that time of year again ... Advertisements that sound 'too good to be true' multiply during holiday season and the NAD is here to help

In a first interventional clinical trial, This phenotypic information alone led to strongly improved treatment of patients with aggressive hematologic malignancies.enabled by this high-throughput, Predictive, And phenotypic information, I here propose to identify the molecular and cellular systems that govern treatment response individuality in cancer.

Sciper: Studying cancer individuality by personal and predictive drug screening and differential omics

The results of the study will inform interventional clinical trial design and enrollment for EDIT-101.

United States : Editas Medicine Announces Third Quarter 2017 Results and Update

Tenders are invited for this funding opportunity announcement (foa) solicits applications that propose to conduct time-sensitive mechanistic ancillary studies related to the niams mission in conjunction with privately or publicly funded, ongoing interventional clinical trials. the ongoing parent project has to be an interventional clinical trial that can provide a cohort of well-characterized patients, infrastructure, data, and biological samples.

Mechanistic Ancillary Studies To Ongoing Interventional Clinical Trials (r01)

"The EU-PNAFLD registry will facilitate recruitment into interventional clinical trials as well as imaging, biomarker, and translational studies, plus allow greater understanding of the long-term natural history of NAFLD.

New blood test on horizon for paediatric liver disease

Another important goal of the Network will be to actively support clinical research into risk factors and biomarkers of early and severe disease phenotypes, and provide a platform for innovative interventional clinical trials aimed at improving or stabilizing kidney functions and preventing progressive renal failure in adults and children with rare kidney diseases.

European Rare Kidney Diseases Reference Network

They concluded that supplementation of Vitamin D, a minimum dose of 100ug/d (4000 IU/d), significantly reduces fasting blood glucose, HbA1c, and homeostatic model assessment of insulin resistance (HOMA-IR) index, and helped to control glycaemic response and improve insulin sensitivity in T2DM patients.21 These conflicting conclusions led to some more interventional clinical trials and a landmark meta-analysis reported that there is no substantial or statistical evidence to date that vitamin D in its active form has a clinical and therapeutic role in treatment of T2DM patients in addition to the conventional anti-diabetic medicines.22

Efficacy of oral vitamin D on glycated haemoglobin (HbA1c) in type 2 diabetics having vitamin D deficiency - A randomized controlled trial