The pattern suggested smoking related interstitial disease
However, two series of patients undergoing lung biopsy for diffuse interstitial disease
reported PLCH in 3%-5% of all diffuse lung disease biopsies, in comparison with sarcoidosis, which was found in 12.
In patients with pathologically proven CMV pneumonia, CXRs usually show bilateral, reticular, interstitial disease
that classically begins in the periphery of the lower lobes and spreads centrally and superiorly, as seen in 3 of our patients.
The classic presentation of PCP is bilateral perihilar interstitial disease
that becomes progressively diffuse and causing extensive cavitations and lung destruction.
The patient's past medical history included Crohn's disease diagnosed 4 years prior, recurrent pancreatitis, pancreas divisum, chronic renal failure secondary to interstitial disease
, and papillary necrosis.
The decision to pursue a VATS biopsy was made by their attending pulmonologist, based on poor respiratory function with high-resolution computerized tomography (HRCT) changes suggestive of interstitial disease
, marked worsening of the patient's condition, or any nodular radiologic patterns.
Six patients had septic emboli, and the rest had multifocal air space disease or interstitial disease
Furthermore, the presence of interstitial disease
was not strongly correlated with measured exposure levels, suggesting that susceptibility factors other than total dose are important in the causation of disease.
Currently, there are no reliable statistics, to my knowledge, concerning the frequency of accelerated phase in occult chronic interstitial disease
However, given the confusion that often exists with regard to diffuse lung diseases, the art of interpreting the chest radiograph for the detection and characterization of interstitial disease
has become less appreciated.
Alveolar macrophages Obstructive diseases, drug reactions, respiratory bronchiolitis, smoking-related interstitial disease
(respiratory bronchiolitis-associated interstitial lung disease, desquamative interstitial pneumonia, pulmonary Langerhans cell histiocytosis) 3.