interstitial cell


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Leydig cell

The testosterone-secreting cell of the testis which is located in clusters in the interstitium between the seminiferous tubules. Leydig cells are large and have centrally located nuclei, eosinophilic cytoplasm and numerous lipid-filled cytoplasmic vacuoles.

Function
Male sexual differentiation, pubertal androgenisation, support for fertility.
 
Physiology 
Secrete testosterone, androstenedione and dehydroepiandrosterone (DHEA) in response to central (pituitary) stimulation by luteinising hormone, which activates cholesterol desmolase.

interstitial cell

Any of the many cells found in connective tissue of the ovary, in the seminiferous tubules of the testes, and in the medulla and cortex of the kidney. The cells in the testes and ovaries produce hormones such as testosterone and estrogen.
See also: cell
References in periodicals archive ?
Triguero, "Interstitial cells of Cajal in the urethra are cGMP-mediated targets of nitrergic neurotransmission," American Journal of Physiology Renal Physiology, vol.
[sup][1] Although TEM alone allowed identification of TCs, caution should be taken to differentiate TCs from other interstitial cells in tunica adventitia.
Chen, "Interstitial cells of cajal: Update on basic and clinical science," Current Fungal Infection Reports, vol.
Although the embryologic origin is unclear, it has been shown that interstitial cells originate from the mesenchymal cells.[sup.3]
Sanders, "A case for interstitial cells of Cajal as pacemakers and mediators of neurotransmission in the gastrointestinal tract," Gastroenterology, vol.
During the prolonged cuticle stage, the major events are the conversion of the outer layer of blastomeres into a layer closely resembling the adult ectoderm and the appearance of the interstitial cell lineage [ILLUSTRATION FOR FIGURES 41-43 OMITTED].
Migration of the nematoblasts begins by 13 h postfertilization, and these cells are the first of the interstitial cell system to appear in the ectoderm (by 14 h postfertilization) of the planula.
In adult male rats, decrease in weight of testes, degeneration and necrosis of spermatogenic and interstitial cells of leydig and absence of spermatogenesis at high doses are all manifestations of toxic effect of lead5.
The theca of atretic mature oocytes was hypertrophied and persisted to form the interstitial cells, whereas the granulosa cells were regressed and disappeared.
The membranous staining pattern in interstitial cells was considered as positive.
They originate from the interstitial cells of Cajal, whose function is to act as pacemaker cells.