hybridoma

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hybridoma

 [hi″brĭ-do´mah]
a somatic cell hybrid formed by fusion of normal lymphocytes and tumor (lymphoma) cells. B cell hybridomas are the most useful source of monoclonal antibodies; the hybridoma cells are able to produce antibody like the normal parent and to proliferate indefinitely in culture like the parent tumor cells.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

hy·brid·o·ma

(hī'brid-ō'mă),
A tumor of hybrid cells used in the in vitro production of specific monoclonal antibodies; produced by fusion of an established tissue culture line of lymphocyte tumor cells (for example, mouse plasmacytoma cells) and specific antibody-producing cells (for example, splenocytes from specifically immunized mice). Fusions are accomplished by use of polyethylene glycol or other methods.
[G. hybris, violation, wantonness, + -ōma, tumor]
Farlex Partner Medical Dictionary © Farlex 2012

hybridoma

(hī′brĭ-dō′mə)
n.
A cell that is produced in the laboratory by fusing an antibody-producing lymphocyte (which does not readily divide) with a nonantibody-producing cancer cell (which divides rapidly). The hybridoma proliferates and produces a continuous supply of a specific monoclonal antibody.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

hy·brid·o·ma

(hī'brid-ō'mă)
A tumor of hybrid cells used in the production in vitro of specific monoclonal antibodies; produced by fusion of an established tissue culture line of lymphocyte tumor cells and specific antibody-producing cells.
[G. hybris, violation, wantonness, + -ōma, tumor]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

hybridoma

A cell line (CLONE) formed by the fusion of two or more different types of cells, such as a B LYMPHOCYTE and a lymphoid tumour cell (myeloma). Malignant tumours can be immortal so a hybridoma, suitably nourished, can continue permanently exercising the function of the B lymphocyte to produce specific antibodies (MONOCLONAL ANTIBODIES).
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

hybridoma

a cell made by fusing an antibody-producing B-CELL with a CANCER cell. The cancer cell contributes the ability to divide indefinitely, while the antibody cell contributes the ability to synthesize large amounts of a single antibody A hybridoma CLONE forms as a result of division of this hybrid, and can be maintained indefinitely in culture, producing large amounts of pure antibody The antibodies produced by a specific hybridoma clone are identical, they are MONOCLONAL ANTIBODIES.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005