In the case of a mild pandemic (R (0) = 1-65), we projected antibiotic use to increase by a negligible 1 % over
interpandemic use of the same antibiotics reported for England in 2007-2008 [95% reference range (RR), 0.4-23%; for estimated background antibiotic use during
interpandemic periods, see Supplemental Material, Table 5 (doi: 10.1289/ehp.
"The control of future pandemic and
interpandemic influenza will necessarily rely on each individual state's plan to vaccinate persons and detect and contain this disease," the investigators wrote (Emerg.
(51) One article in the Journal of Public Health Policy pointed out that "almost 40% of the world's supply of
interpandemic influenza vaccines is used in countries that do not produce their own vaccines." (52) Below are some issues that particularly impact the most affected countries in Asia, and other parts of the world.
Phases one and two are referred to as the
Interpandemic Period; three, four, and five are Pandemic Alert; and phase six represents a fully evolved global influenza pandemic.
TABLE 1 WHO global pandemic phases
INTERPANDEMIC PERIOD Phase 1 No new influenza virus subtypes have been detected in humans.
He noted a few of the advantages to LANIs: onetime-only therapy, once-weekly prophylaxis, and an optimal use for
interpandemic cases.
Stockpiles in hospitals, for example, would facilitate rapid treatment of ill patients in a pandemic but might also allow the periodic use of some material for the treatment of
interpandemic seasonal influenza to avoid wastage due to an expiring stockpile (36).
(45) One article in the Journal of Public Health Policy pointed out that "almost 40% of the world's supply of
interpandemic influenza vaccines is used in countries that do not produce their own vaccines." (46) Below are some issues that particularly impact the most affected countries in Asia, and other parts of the world.
He noted a few of the advantages to LANIs: one-time-only therapy, once-weekly prophylaxis, and an optimal use for
interpandemic cases.
Current policy surrounding intervention planning for pandemic and
interpandemic influenza is informed by estimates and simulations that arbitrarily assume a constant rate of asymptomatic infection in the range of 30%-50%.
WHO Pandemic Phases Phase Description Overarching Public Health Goals
Interpandemic Period Phase 1 No new influenza virus Strengthen global influenza strains have been detected pandemic preparedness at in humans.