Smith et al., "Targeting and crossing of the human maternofetal barrier by Listeria monocytogenes: Role of internalin
interaction with trophoblast E-cadherin," Proceedings of the National Acadamy of Sciences of the United States of America, vol.
In the mouse model infected with the internalin
A mutant recombinant strain of L.
(2010), showed that InlC (internalin
family) impairs phosphorylation and delays I[kappa]B degradation often induced by TNF-[alpha], abrogating activation of NF-[kappa]B.
Listeria monocytogenes internalin
and E-cadherin: from bench to bedside.
Like many other microbes, Listeria manufactures a couple of hooks (Listeria's are known as Internalin
A and Internalin
B) that grab onto specific molecules protruding from cells of the intestinal lining.
monocytogenes based on genetic loci in several genes: the hemolysin (hlyA), internalin
(inlA), positive regulatory factor (prfA), and actin polymerization (actA1, actA2) genes.
** A membrane protein called internalin
mediates invasion of the host cell by Listeria bacteria.
monocytogenes virulence mechanisms has shown that certain mutations in the inlA gene, which encodes for internalin
(a membrane-anchored protein responsible for L.
11:00 COMPARISON OF ATTACHMENT STRENGTH OF LISTERIA MONOCYTOGENES AND ITS INTERNALIN
LIPI-2 comprises 10 internalin
genes and the sphingomyelinase gene smcL and is perfectly conserved within L.