The starting dose of Lantus is often half the total units of intermediate-acting insulin
taken per day in the morning and evening.
The pharmacist can use the information on durations of action for the intermediate-acting insulins
shown in Table 3, to instruct the patient on how this insulin regimen provides basal levels of insulin required to maintain proper energy utilization in the cells.
Because food or caloric intake requires insulin at the time of ingestion to facilitate glucose transport across the cell membrane, rapid-acting insulin should be administered before each meal (in 3 daily doses if the patient is also taking a long-acting or intermediate-acting insulin
, or 6 times a day if used without basal insulin).
Although not specifically approved for this purpose by the Food and Drug Administration, fast-acting insulin analogs are routinely used in this patient population along with intermediate-acting insulins
, such as NPH insulin.
Instead, it is considered an alternative to an insulin pump or intermediate-acting insulin
such as NPH.
1c] levels above 8% despite maximal treatment with combination oral agents, and with the addition of bedtime injections of intermediate-acting insulin
Conventional insulin therapy involves administering 1 or 2 injections a day of intermediate-acting insulin
with or without small amounts of regular insulin.
NPH, an intermediate-acting insulin
, is generally used to provide a basal insulin level over the course of the day.
By combining the benefits of the rapid-acting Humalog with an intermediate-acting insulin
, Humalog Mix75/25 provides blood glucose control throughout the day -- at mealtime, between meals, and at nighttime.