intermediate-acting insulin


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intermediate-acting insulin

Etymology: L, inter + mediare, to divide, activus, active
a preparation of synthetic human or pork insulin to which zinc has been added under specific chemical conditions that has an intermediate range of action. Neutral Protamine Hagedorn insulin starts to work about 60 to 90 minutes after injection, peaks 4 to 12 hours after injection, and lasts about 18 hours. Lente Insulin has a similar action time. See also insulin. Compare long-acting insulin, short-acting insulin.
References in periodicals archive ?
Although not specifically approved for this purpose by the Food and Drug Administration, fast-acting insulin analogs are routinely used in this patient population along with intermediate-acting insulins, such as NPH insulin.
In patients with type 2 diabetes who require none or just one evening or nighttime injection of intermediate-acting insulin to control the fasting glucose level, an oral agent capable of stimulating an insulin release sufficient to cover the meal or delay the absorption of glucose from the intestine (bolus agents) should be used.
By combining the benefits of the rapid-acting Humalog with an intermediate-acting insulin, Humalog Mix75/25 provides blood glucose control throughout the day -- at mealtime, between meals, and at nighttime.

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