interleukin-9


Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to interleukin-9: Interleukin-13

in·ter·leu·kin-9

(in'tĕr-lū'kin),
A cytokine derived from T cells that causes IL-2/Il-4-independent growth and proliferation of T cells.

IL9

A gene on chromosome 5q31.1 that encodes interleukin-9, a cytokine which regulates various haematopoietic cells, stimulating cell proliferation and preventing apoptosis. IL9 acts via interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins, linking it to various biological processes.
 
Molecular pathology
IL9 is a candidate gene for asthma.

in·ter·leu·kin-9

(in'tĕr-lū'kin)
A cytokine derived from T cells that causes growth and proliferation of T cells.

interleukin-9

A CYTOKINE produced by T LYMPHOCYTES (T cells) that promotes the growth and proliferation of T cells.
References in periodicals archive ?
The researchers next treated melanoma-bearing mice with T helper cell 9 (TH9), an immune cell that produces interleukin-9.
These include squalamine, an anti-angiogenesis treatment for eye disease and cancer; interleukin-9 antibody, a respiratory treatment based on the discovery of a genetic cause of asthma; and LOMUCIN, a mucoregulator to treat the overproduction of mucus and secretions involved in many forms of chronic respiratory disease.
Genaera Corporation (Plymouth Meeting, PA) announced issuance by the United States Patent and Trademark Office of United States Patent 6,645,486 covering claims for reducing the activity of interleukin-9 comprising administering a conjugate of IL-9 and a carrier sufficient to induce production of IL-9 specific antibodies which bind to and reduce IL-9 activity.