IL21

(redirected from interleukin-21 isoform)

IL21

A gene on chromosome 4q26-q27 that encodes IL-21, a cytokine with immunoregulatory activity that may promote the transition between innate and adaptive immunity. IL21 induces the production of IgG1 and IgG3 in B cells, and may play a role in proliferation and maturation of natural killer cells in synergy with IL15. It is also a less preferred gene symbol for what is now designated as IL17C (see there), as well as IL22 (see there).