IL2RA

(redirected from interleukin-2 receptor subunit alpha)

IL2RA

A gene on chromosome 10p15-p14 that encodes the alpha subunit of interleukin-2 (IL-2) receptor, which forms either a heterodimer with the beta subunit, resulting in a receptor with intermediate-affinity for IL-2, or a heterotrimer with beta and gamma subunits, resulting in a high-affinity IL-2 receptor.

Molecular pathology
Genetic variations in IL2RA are associated with susceptibility to diabetes mellitus insulin-dependent type 10.
References in periodicals archive ?
Global Markets Direct's, 'Interleukin-2 Receptor Subunit Alpha (IL-2 Receptor Subunit Alpha or TAC Antigen or p55 or CD25) - Pipeline Review, H1 2016', provides in depth analysis on Interleukin-2 Receptor Subunit Alpha (IL-2 Receptor Subunit Alpha or TAC Antigen or p55 or CD25) targeted pipeline therapeutics.
The report provides comprehensive information on the Interleukin-2 Receptor Subunit Alpha (IL-2 Receptor Subunit Alpha or TAC Antigen or p55 or CD25), targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
* The report provides a snapshot of the global therapeutic landscape for Interleukin-2 Receptor Subunit Alpha (IL-2 Receptor Subunit Alpha or TAC Antigen or p55 or CD25)