interleukin-18

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Related to interleukin-18: Il-18

in·ter·leu·kin-18

(in'tĕr-lū'kin),

A cytokine produced by macrophages; a potent inducer of interferon-γ by T cells and NK cells.

IL18

A gene on chromosome 11q22.2-q22.3 that encodes IL-18, a proinflammatory cytokine that increases natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.

in·ter·leu·kin-18

(in'tĕr-lū'kin)

A cytokine made by macrophages; a potent inducer of interferon-γ by T cells and natural killer cells.

interleukin-18

Abbreviation: IL-18

A cytokine produced by macrophages that stimulates the production of gamma interferon and other chemical mediators that enhance cell-mediated immune responses. It is similar in structure to IL-1.

interleukin-18

IL-18

A cytokine produced by macrophages that stimulates the production of gamma interferon (IFN?) and other chemical mediators that enhance cell-mediated immune responses. Interleukin-18 is similar in structure to IL-1.

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References in periodicals archive ?

Interleukin-18 overexpression as a hallmark of the activity of autoimmune inflammatory myopathies.

Serum Interleukin-18 Level is Associated With Disease Activity and Interstitial Lung Disease in Patients With Dermatomyositis

Calcineurin antagonists inhibit interferon-gamma production by downregulation of interleukin-18 in human mixed lymphocyte reactions.

A case of adult-onset still's disease treated with monitoring of serum tacrolimus levels

Interleukin-18 involvement in hypoxic- ischemic brain injury.

Creatine Monohydrate Supplemented Diets Affect Serum Inflammatory Cytokine Levels (IL-6 and IL-18) in Female Albino Mice Following Neonatal Hypoxic Ischemic Encephalopathy

Interleukin-18 controls energy homeostasis by suppressing appetite and feed efficiency.

Inflammatory biomarkers, physical exercise and childhood obesity: review/Marcadores inflamatorios, exercicio fisico e obesidade infantil: uma revisao

A novel role for interleukin-18 in adhesion molecule induction through NF kappa B and phosphatidylinositol (PI) 3 -kinase-dependent signal transduction.

Association of CD40 and IL-18 gene variants with kidney transplant rejection in Iranian patients

Altered expression of interleukin-18 in the ectopic and eutopic endometrium of women with endometriosis.

Effects of IFN-[gamma] on IL-18 expression in pregnant rats and pregnancy outcomes

Interleukin-18 serum levels in inflammatory bowel diseases: correlation with disease activity and inflammatory markers.

Inflammatory bowel disease: diagnosis and research trends: the clinical lab is playing an increasingly important role

Serum levels of interleukin-18 in patients with stable and unstable angina pectoris.

Serum levels of interleukin (IL)-13, IL-17 and IL-18 in patients with ischemic heart disease/Iskemik kalp hastaligi olan hastalarda serum interlokin (IL)-13, IL-17 ve IL-18 duzeyleri

Abbott scientists reported in the November 2007 issue of Nature Biotechnology, a scientific journal, that they created antibodies that latched onto Interleukin-12 and Interleukin-18, two components of the immune system.

The drug pipeline; Abbott striving for an edge in the race to develop new medicines

3]-exposed rats have shown that macrophages release tumor necrosis factor-[alpha] and interleukin-18, leading, through a series of steps, to NO production and ultimately tissue injury.

Workgroup report: indoor chemistry and health

Chapter 20: Interleukin-18 in Metabolic Syndrome and Diabetes

Research and Markets: Nutritional And Therapeutic Interventions For Diabetes And Metabolic Syndrome

The underlying pathophysiology of PRES complicated with autoimmune diseases are as follows: theories including dysfunction of autoregulatory cerebral perfusion mechanisms and endothelia, inflammasome activation of interleukin-18 and neutrophil extracellular trap formation and the presence of autoantibodies (N-methyl-D-aspartate receptor and anti-aquaporin 4) were studied.

An Atypical Syndrome in an Elderly Patient With Systemic Lupus Erythematosus, Sjogren Syndrome, and Primary Biliary Cirrhosis