interleukin-18

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Related to interleukin-18: Il-18

in·ter·leu·kin-18

(in'tĕr-lū'kin),

A cytokine produced by macrophages; a potent inducer of interferon-γ by T cells and NK cells.

Farlex Partner Medical Dictionary © Farlex 2012

IL18

A gene on chromosome 11q22.2-q22.3 that encodes IL-18, a proinflammatory cytokine that increases natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.

in·ter·leu·kin-18

(in'tĕr-lū'kin)

A cytokine made by macrophages; a potent inducer of interferon-γ by T cells and natural killer cells.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

interleukin-18

Abbreviation: IL-18

A cytokine produced by macrophages that stimulates the production of gamma interferon and other chemical mediators that enhance cell-mediated immune responses. It is similar in structure to IL-1.

interleukin-18

IL-18

A cytokine produced by macrophages that stimulates the production of gamma interferon (IFN?) and other chemical mediators that enhance cell-mediated immune responses. Interleukin-18 is similar in structure to IL-1.

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References in periodicals archive ?

Soluble interleukin-18 receptor complex is a novel biomarker in rheumatoid arthritis.

Gene expression of Interleukin-18 in rheumatoid arthritis patients on disease modifying anti-rheumatic drug therapy

Interleukin-18 promoter polymorphisms and risk of ischemic stroke.

Increased Expression of Interleukin-18 mRNA is Associated with Carotid Artery Stenosis

Interleukin-18 involvement in hypoxic-ischemic brain injury.

The Expression of IL-18R[alpha] in Inferior Mesenteric Ganglion of Female Goat

Box plots of (a) urinary neutrophil gelatinase-associated lipocalin (NGAL), (b) interleukin-18 (IL-18), and (c) kidney injury molecule-1 (KIM-1) by acute kidney injury (AKI) status.

Novel renal biomarker evaluation for early detection of acute kidney injury after transcatheter aortic valve implantation

Genetic polymorphisms -137 (rs187238) and -607 (rs1946518) in the interleukin-18 promoter may not be associated with development of hepatocellular carcinoma.

Evaluation of the Role of -137G/C Single Nucleotide Polymorphism (rs187238) and Gene Expression Levels of the IL-18 in Patients with Coronary Artery Disease

Dinarello, "Interleukin-18 and the pathogenesis of inflammatory diseases," Seminars in Nephrology, vol.

Predictive Role of Interleukin-18 in Liver Steatosis in Obese Children

Hagberg, "Interleukin-18 involvement in hypoxic-ischemic brain injury," The Journal of Neuroscience, vol.

Effects of Kudiezi Injection on Serum Inflammatory Biomarkers in Patients with Acute Cerebral Infarction

Okamura et al., "Interleukin-18 enhances the production of interleukin-8 by eosinophils," European Journal of Immunology, vol.

Cutting Edge: Biomarkers for Chronic Spontaneous Urticaria

Interleukin-18 (IFNgamma-inducing factor) induces IL-8 and IL-1beta via TNFalpha production from non-CD14+ human blood mononuclear cells.

Serum Interleukin-18 Level is Associated With Disease Activity and Interstitial Lung Disease in Patients With Dermatomyositis

[12] reported that levels of interleukin-18, which is largely regarded as a product of macrophages [13], are significantly higher during the active stage of pediatric ISSNS compared to remission and controls.

Apolipoprotein C-I Levels Are Associated with the Urinary Protein/Urinary Creatinine Ratio in Pediatric Idiopathic Steroid-Sensitive Nephrotic Syndrome: A Case Control Study

They hypothesized that interleukin-18 may have an important role in the pathogenesis of HLH with SLE.

Successful Treatment of Hemophagocytic Lymphohistiocytosis Associated with Lupus Nephritis by Using Mycophenolate Mofetil

Nishizaki, "Interleukin-18 stimulates synaptically released glutamate and enhances postsynaptic AMPA receptor responses in the CA1 region of mouse hippocampal slices," Brain Research, vol.

IL-33 Acts to Express Schaffer Collateral/CA1 LTP and Regulate Learning and Memory by Targeting MyD88