Also found in: Dictionary, Thesaurus, Encyclopedia.
A cytokine derived from T cells that stimulates T cell proliferation and NK cell activation.
a growth factor that enhances peripheral blood T cell production.
IL15A gene on chromosome 4q31 that encodes interleukin-15, a cytokine which regulates T and natural killer cell activation and proliferation. IL15 shares many biological activities with IL-2: they both bind common haematopoietin receptor subunits and may compete for the same receptor, thus having a ying-yang relationship with each other. IL15 activates JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5 and STAT6.
A cytokine derived from T cells that stimulates T-cell proliferation and natural killer cell activation.