Node, "Increased interleukin-13
levels in patients with chronic heart failure," International Journal of Cardiology, vol.
Eosinophils and CCR3 regulate interleukin-13
transgene-induced pulmonary remodeling.
McKenzie, "A distinct role for interleukin-13
in Th2-cell-mediated immune responses," Current Biology, vol.
Byrd, "Secondary structure and backbone resonance assignments for human interleukin-13
," Journal of Biomolecular NMR, vol.
Lipoxin A4 also discouraged type 2 innate lymphoid cells from promoting inflammation by blocking interleukin-13
levels in serum from patients with Hodgkin disease and healthy volunteers.
IL-13R alpha2 is believed to be a naturally occurring decoy receptor, capable of binding the cytokine Interleukin-13
(IL-13), but not transmitting a signal to the inside of the cell.
Dupixent is a human monoclonal antibody that inhibits the signaling of interleukin-4 (IL-4) and interleukin-13
(IL-13), two key proteins that play a central role in type 2 inflammation that underlies specific types of asthma as well as several other allergic diseases.
The approval of dupilumab--an interleukin-4 and interleukin-13
inhibitor and the first biologic to become available for the treatment of atopic dermatitis--has revolutionized the therapy of adults with moderate to severe disease.
has been shown to be highly expressed in AD skin on immunohistochemistry and transcriptome studies, and IL-13 gene polymorphisms are associated with increased AD risk.
Atopic dermatitis; eczema; filaggrin; filaggrin null mutation; ILC2s; interleukin-13
; interleukin-25; nuocytes; toll-like receptors; type 2 innate lymphoid cells
induces goblet cell differentiation in primary cell culture from guinea pig tracheal epithelium," American Journal of Respiratory Cell and Molecular Biology, vol.