Trinchieri, "Proinflammatory and immunoregulatory functions of interleukin-12
," International Reviews of Immunology, vol.
Parameters IL-12p40 r P value Age (days) 0.075 0.629 Total bilirubin (mg/dl) 0.198 0.089 Direct bilirubin (mg/dl) 0.114 0.33 Albumin (g/dl) -0.0285 0.469 Alanine aminotransferase (U/l) -0.02 0.865 Aspartate aminotransferase (U/l) -0.08 0.497 Alkaline phosphatase (U/l) 0.087 0.457 Gamma-glutamyl transpeptidase (U/l) -0.042 0.723 Prothrombin time (seconds) 0.224 0.053 Hemoglobin (g/dl) -0.183 0.117 White blood cells (x[10.sup.3]/[mm.sup.3]) 0.102 0.385 Platelets (x[10.sup.3]/[mm.sup.3]) -0.013 0.912 Grade of liver fibrosis -0.06 0.607 Necroinflammatory activity -0.107 0.362 BA: biliary atresia; IL-12p40: interleukin-12
p40 subunit; r: correlation coefficient.
and the regulation of innate resistance and adaptive immunity," Nature Reviews Immunology, vol.
modulates the protective immune response in SCID mice infected with Histoplasma capsulatum," Infection and Immunity, vol.
Chyczewska, "Increased levels of interleukin-12
and interleukin-18 in bronchoalveolar lavage fluid of patients with pulmonary sarcoidosis," Journal of Physiology and Pharmacology, vol.
Cytokine therapy of cutaneous T-cell lymphoma: Interferons, interleukin-12
, and interleukin-2.
The study authors conclude: "These results may suggest a beneficial immunostimulatory effect of short-term Chlorella supplementation which enhances the [Natural Killer] cell activity and produces interferon-gamma and interleukin-12
as well as interleukin-1beta, the Th-1 cell-induced cytokines in healthy people."
Comparison of maternal serum levels of interleukin-10, interleukin-12
, and interleukin-2 in normal and preeclamptic pregnancies.
With UVA, silibinin kills; with UVB, it protects, in this case by increasing cells' expression of the protein interleukin-12
, which works to quickly repair damaged cells.
Schaub et al., "Regulation of the inflammatory response in animal models of multiple sclerosis by interleukin-12
," Critical Reviews in Immunology, vol.
The drug inhibits two inflammatory proteins called interleukin-12
(Nasdaq:ZIOP), a biopharmaceutical company with small molecule and synthetic biology approaches to new cancer therapies, has announced the presentation of preclinical data demonstrating the significant anti-tumor activity of Interleukin-12
(IL-12) and interferon alpha (IFNα), two proteins involved in immune response to cancers, expressed in vivo utilizing a regulated gene system.