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A cytokine and growth factor derived from bone marrow stromal cells (endothelial cells, macrophages, and preadipocytes) that stimulates increased plasma concentrations of acute-phase proteins and is a growth factor with multiple hematopoietic effects.
Farlex Partner Medical Dictionary © Farlex 2012
IL11A gene on chromosome 19q13.3-q13.4 that encodes interleukin-11, a member of the gp130 family of cytokines, which drive the assembly of multi-subunit receptor complexes, all of which contain at least one molecule of the transmembrane signalling receptor IL6ST. IL11 directly stimulates the proliferation of haematopoietic stem cells and megakaryocyte progenitor cells, and it induces megakaryocyte maturation resulting in increased platelet production.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
A cytokine derived from bone marrow stromal cells (endothelial cells, macrophages, and preadipocytes) that stimulates increased plasma concentrations of acute phase proteins.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
interleukin-11A CYTOKINE produced by bone marrow stromal cells that promotes the induction of ACUTE PHASE PROTEINS.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005