IFITM3

(redirected from interferon-induced transmembrane protein 3)

IFITM3

A gene on chromosome 11p15.5 that encodes an interferon-induced protein, which mediates innate cellular immunity against viral pathogens—e.g., influenza A H1N1, West Nile, and dengue viruses—by inhibiting the early steps of viral replication.
 
Molecular pathology
IFITM3 mutations are linked to increased susceptibility to viral infections.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Investigators have now shown that reducing levels of one antiviral factor called interferon-induced transmembrane protein 3 (IFITM3) makes cultured cells highly sensitive to ZIKV infection.
Hang, "S-palmitoylation and ubiquitination differentially regulate interferon-induced transmembrane protein 3 (IFITM3)-mediated resistance to influenza virus," Journal of Biological Chemistry, vol.
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