interferon alpha


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in·ter·fer·on al·pha

the major interferon made by virus-induced leukocytes; several different subtypes exist that are elaborated by leukocytes in response to viral infection or to stimulation with double-stranded RNA. There are 14 genes on the short arm of chromosome 9 that code for these substances in humans. IFN-α-2A and -2B are protein products made by recombinant DNA techniques and are used as antineoplastic agents.

interferon alpha

Interferon alpha

Potent immune-defense protein; used as an anti-cancer drug.

in·ter·fer·on al·pha

(intĕr-fēron alfă)
The major interferon made by virus-induced leukocytes; several subtypes exist that are elaborated by leukocytes in response to viral stimulation.
References in periodicals archive ?
Keywords: Hepatitis C virus, Hepatitis B virus, Interferon alpha receptor 1, Interferon alpha receptor 2, Interferon therapy response, Signal transducer and activator of transcription1.
A strategy for high-level expression of soluble and functional human interferon alpha as a GST-fusion protein in E.
Despite the development of thyroid disorders (overt and sub-clinical), patients completed their antiviral therapy with Interferon alpha and ribavirin.
Cytokine and Psychopathology: lessons from interferon alpha. Biol Psychiatry 2004; 56: 819-24.
[Pericarditis secondary to interferon alpha in chronic hepatitis C].
Caption: The lethal Ebola virus (shown in a false-color micrograph) appears susceptible to a combination treatment of antibodies and the antiviral protein interferon alpha delivered by an inactivated virus, a study in monkeys shows.
Poole, "Interferon alpha in systemic lupus erythematosus," Journal of Biomedicine and Biotechnology, vol.
Methods: This was a quasi - experimental study in which patients of both sexes between ages 20 - 49 were randomly allocated to receive three different formulations of interferon alpha 2b in three groups, I, II, and III, after giving them first dose of three million units of interferon alpha 2b sub-cutaneously.
[10] Retnoningrum, D.S., "et al", 2010, "Construction of synthetic open reading frame encoding human interferon alpha 2b for high expression in Escherichia coli and characterization of its gene product," J.
One month before, the FDA had approved sorafenib (brand name Nexavar) in patients with RCC in whom previous therapy (usually cytokines such as interferon alpha or interleukin-2) had failed.
Contrast echocardiography may be a useful non-invasive technique for detecting PAVM and the interferon alpha may be first treatment option for patients with IHHE and PAVM.