intercellular adhesion molecule-1

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in·ter·cel·lu·lar ad·he·sion mol·e·cule-1 (ICAM-1),

a glycoprotein that is expressed on a variety of cells. The natural ligand for ICAM-1 is LFA-1, but it also serves as the cellular receptor for rhinoviruses in respiratory epithelium.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
Intercellular adhesion molecule-1 (ICAM-1) expression and cell signaling cascades.
Tamura et al., "New indices of ischemic heart disease and aging: Studies on the serum levels of soluble intercellular adhesion molecule-1 (ICAM-1) and soluble vascular cell adhesion molecule-1 (VCAM-1) in patients with hypercholesterolemia and ischemic heart disease," Atherosclerosis, vol.
Abbreviations AS: Atherosclerosis AP-1: Activator protein-1 CCK-8: Cell count kit-8 Cav-1: Caveolin-1 CAM: Caldesmon ET-1: Endothelin-1 eNOS: Endothelial nitric oxide synthase IL-1[beta]: Interleukin-1[beta] IL-6: Interleukin-6 IL-8: Interleukin-8 ICAM-1: Intercellular adhesion molecule-1 I[kappa]B[alpha]: Inhibitory kappa B [alpha] IKK[beta]: Inhibitory kappa B kinase [beta] NO: Nitric oxide NF-[kappa]B: Nuclear factor-[kappa]B p38 MAPK: p38 mitogen-activated protein kinase ROS: Reactive oxygen species SelS: Selenoprotein S SNP: Single nucleotide polymorphism siRNA: Small interfering RNA TNF-[alpha]: Tumour necrosis factor-alpha VSMCs: Vascular smooth muscle cells VCAM-1: Vascular cell adhesion molecule-1
ABO polymorphism increases the susceptibility to myocardial infarction through some pathways, such as increasing vWF level, soluble intercellular adhesion molecule-1 level, soluble P-selectin level, and soluble E-selectin level [20].
Expression of intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 in the pig coronary artery injury model: Comparison of plain old balloon angioplasty and stent implantation.
"At weeks 1 and 2, we found large associations between HIF-2a and increases in a number of proinflammatory cytokines including IL-8 and intercellular adhesion molecule-1," a protein that facilitates leukocyte migration.
E-selectin and intercellular adhesion molecule-1 are released by activated human endothelial cells in vitro.
Iiyama et al., "Patterns of vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 expression in rabbit and mouse atherosclerotic lesions and at sites predisposed to lesion formation," Circulation Research, vol.
Association between the polymorphisms in intercellular adhesion molecule-1 and the risk of coronary atherosclerosis: a case-controlled study.
Shiina et al., "Platelet-derived growth factor is apotent stimulator of expression of intercellular adhesion molecule-1 in human arterial smooth muscle cells," Biochemical and Biophysical Research Communications, vol.
Increased soluble vascular cell adhesion molecule-1 plasma levels and soluble intercellular adhesion molecule-1 during antiretroviral therapy interruption and retention of elevated soluble vascular cellular adhesion molecule-1 levels following resumption of antiretroviral therapy.

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