ICAM5

(redirected from intercellular adhesion molecule 5)

ICAM5

A gene on chromosome 19p13.3-p13.2 that encodes a protein of the intercellular adhesion molecule (ICAM) family of type-I transmembrane glycoproteins. ICAM5 is expressed on the surface of telencephalic neurones and displays 2 types of adhesion: homophilic binding between neurones and heterophilic binding between neurones and leukocytes. It may play a critical role in neuron-microglial cell interactions during normal development or be involved in neurodegenerative disease.
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References in periodicals archive ?
Cell adhesion molecule Abbreviation Neural cell adhesion molecule NCAM Polysialated neural cell adhesion molecule PSA-NCAM Neuronal cell adhesion molecule NRCAM Immunoglobulin super family IGSF Synaptic cell adhesion molecule SYNCAM Intercellular adhesion molecule 5 ICAM5 Cadherin 13 CDH13 Neurexin 3 NRXN3 Neurexin 2[beta] NRXN2[beta] Neuroligin 3 NLGN3 Neuroligan 1 NLGN1 Neurexin 3[beta] NRXN3[beta] Protein tyrosine phosphatase receptor D PTPRD Protein tyrosine phosphatase receptor B PTPRB CUB and Sushi multiple domains 1 CSMD1 Protein tyrosine phosphatase receptor Z 1 PTPRZ1 Table 2: Gene expression changes after repeated cocaine treatment.
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