Thus the binding interaction is groove binding mode but not involved in intercalative
binding of drug with DNA is associated with hypochromic effect and a large red shift while the groove binding and electrostatic interaction may be associated with hypochromic and/or hyperchromic effect.
Satyanarayana, "Synthesis, DNA interaction and photocleavage studies of ruthenium(II) complexes with 2-(pyrrole) imidazo-[4,5-f]-1,10-phenanthroline as an intercalative
ligand," Transition Metal Chemistry, vol.
Another strategy is based on the intercalative
polymerization of the monomer.
It was suggested that the interaction of metal compounds with DNA of promistigote through intercalative
mode, cause damage to the DNA .
Shchegolikhin, "Thermal properties of polyethylene/ montmorillonite nanocomposites prepared by intercalative
polymerization," Journal of Materials Science, vol.
Resol-layered silicate composites were synthesized by intercalative
polymerization of phenol and formaldehyde in the presence of differently modified clays.
The negative shift in formal potential is believed to be due to the presence of electrostatic interaction between cationic iron moiety and anionic phosphate of the DNA backbone whereas positive shift is indicative of the presence of an intercalative
mode of interaction .
Lu, "Synthesis of polymer-montmorillonite nanocomposites by in situ intercalative
polymerization," Nanotechnology, vol.
Here, we report the synthesis of PLACN with in-house modified and commercially modified clays, yielding high [M.sub.n] (~ 126,000 and -100,000 Da, respectively) within 2 h by in situ intercalative
ring opening polymerization (ROP) of L-lactide.
This method has been used to prepare PVC/PCL/OMMT nanocomposites by combination of intercalative
polymerization of PCL masterbatches and melt blending of PVC with these masterbatches .
Amongst the most used techniques to obtain polymer-platelet like clay nanocomposites are the so-called in situ intercalative
polymerization (23), (24), in which a given monomer is mixed with a clay and then polymerized in situ, allowing the growth of the polymeric chains between the clay platelets; and the melt-processing method (23), in which the polymer is directly mixed with an organically-modified clay in the molten state using conventional thermoplastic processing methods such as extrusion or injection molding.