were present close to developing islet tissue in the twenty specimens of groups A and B and not present in group C.
B, Smooth muscle actin expression in myoepithelial cells of acini and intercalated duct
. C, Smooth muscle myosin heavy chain expression in myoepithelial cells of acini and intercalated duct
Salivary epithelial-myoepithelial Scarcinomas of intercalated ducts
: a clinical, electron microscopic, and immunocytochemical study.
Like the human salivary glands (Amano, 2011; Bruel et al., 2015), the duct system in rodents and rabbits is made up of intercalated ducts
(ID), striated ducts (SD), excretory ducts (ED) and main excretory ducts, with these last ones leading to the main excretory duct (MED) (Fig.
Epithelial-myoepithelial carcinoma of the intercalated ducts
," Virchows Archiv Abteilung A Pathologische Anatomie, vol.
The smallest ducts are comparable to intercalated ducts
but the large ducts for the most part lack the distinguishing features of striated ducts3.
Plenty of intercalated ducts
, striated and excretory ducts are seen scattered.
[1,2] In a normal gland, myoepithelial cells are located between the epithelial cells and the basal lamina of acini and intercalated ducts
.  Some authors believe that myoepithelial cells play a definite role in several salivary gland tumors, such as mixed tumors, adenoid cystic carcinomas, and salivary duct carcinomas.
It has been postulated that these tumours arise from intercalated ducts
and myoepithelial cells (4).
 It is thought to arise from the intercalated ducts
of mucus-secreting glands.
In the classic definition of EMCa, the myoepithelial component consists of polygonal cells with clear cytoplasm, whereas the ductal component is composed of small lumina lined by cuboidal, mildly eosinophilic cells reminiscent of intercalated ducts
. (1-3) However in our previously reported series of 61 cases, (4) we had observed a much broader morphologic spectrum with respect to cytoplasmic characteristics, relative cell type proportion, and pattern of arrangement.