intention-to-treat analysis


Also found in: Acronyms, Wikipedia.

intention-to-treat analysis

method of analyzing results of a randomized controlled trial that includes in the analysis all those cases that should have received a treatment regimen but for whatever reason did not. All cases allocated to each arm of the trial are analyzed together as representing that treatment arm, regardless of whether they received or completed the prescribed regimen.

intention-to-treat an·al·y·sis

(in-ten'shŭn-trēt ă-nal'i-sis)
Method of assessing results of a randomized controlled trial that includes in the analysis all the cases that should have received a treatment regimen but for some reason did not. All cases allocated to each arm of the trial are analyzed together as representing that treatment arm, regardless of whether they received or completed the prescribed regimen.

intention-to-treat analysis

analysis of subject data, according to the experimental intervention allocated by experimental design, whether subjects received the intervention or not; i.e. start data of subjects lost during the trial are recorded as their endpoint data, to avoid sample attrition bias
References in periodicals archive ?
5) Item adherence, n = % Eligibility 74 76 Random allocation 93 96 Concealed allocation 22 29 Similarity at baseline 64 76 Subject blinding 13 5 Therapist blinding 2 3 Assessor blinding 40 34 > 85% follow-up 54 67 Intention-to-treat analysis 19 25 Between-group statistical 88 93 comparison Point and variability 80 92 measures
An Intention-to-Treat analysis was performed including all patients who took at least one dose of TMC435.
Using intention-to-treat analysis, the researchers found no difference in the recurrence rate of pyelonephritis between the groups.
The intention-to-treat analysis revealed a statistically significant improvement in subjects receiving XIFAXAN versus placebo-treated subjects (38% vs.
97) or five birth rates per intention-to-treat analysis (7.
In the intention-to-treat analysis, the highest volumes of PEG (3 L or more) led to greater bowel cleanliness than did lower split-dose volumes (OR, 1.
In the intention-to-treat analysis, the rate of treatment success was 75% in patients randomly assigned to bracing, compared with 42% in those randomly assigned to observation only.
There were no significant differences between the two groups in ADHD symptoms on any assessment, either in the intention-to-treat analysis or the per-protocol analysis, Dr.
Using intention-to-treat analysis, stable anticoagulation control occurred in significantly more patients taking vitamin K supplementation than in patients taking placebo (54% vs 21%; number needed to treat = 3; 95% confidence interval, 2-10).
An intention-to-treat analysis at three years demonstrated trends toward delaying disease progression and decreasing the proportion of male patients demonstrating progression in favor of COPAXONE(R).
In an intention-to-treat analysis, 92% of patients in the low-dose posaconazole group and 81% in the high-dose posaconazole group tested positive for T.
In the primary efficacy intention-to-treat analysis, 79.