integron


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integron

a GENETIC element that has the ability to acquire unrelated GENES, such as ANTIBIOTIC resistance genes, by site-specific integration events. Integrons have been found in PLASMIDS and TRANSPOSABLE GENETIC ELEMENTS and are probably important in the EVOLUTION of GENOMES.
References in periodicals archive ?
Identification of typical class 1 and class 2 integron gene cassettes in clinical isolates of MDR Shigella flexneri in South Indian population.
These isolates were also subjected to susceptibility testing and polymerase chain reaction for four groups of genes including int encoding integron elements, sull and sulll encoding trimethoprim-sulfamethoxazole resistance and smqnr encoding quinolone resistance.
Detection of integron elements and gene groups encoding ESBLs and their prevalence in Escherichia coli and Klebsiella isolated from urine samples by PCR method.
MBLs have recently emerged as one the most worrisome resistance mechanisms as MBL genes are located on integron structures that reside on mobile genetic elements such as plasmids or transposons, which gives them ability for widespread dissemination.
Identification of a new integron harboring blaIMP-10 in carbapenem-resistant Acinetobacter baumannii clinical isolates.
Second dominant group of acquired MBL was VIM [Verona Integron encoded Metallo P-lactamases] [Veronese Imipenemase] type enzyme, which was first described in Verona, Italy from a Pseudomonas aeruginosa isolate in 1997 which was resistant to piperacillin, ceftazidime, imipenem and aztreonam [63].
The genes responsible for the production of MBLs are typically part of class 1 integron structures, which carry other resistance gene cassettes.
Using polymerase chain reaction and sequence, we carefully examined the existence of antibiotic-resistance genes and integron genes in soils and strains.
Trimetoprim, sulfonamidas y cloranfenicol: la resistencia a sulfonamida esta mediada por el gen sul que se encuentran en la region 3'de un integron (9).