ITGA11

(redirected from integrin alpha-11)

ITGA11

A gene on chromosome 15q23 that encodes an alpha integrin—integral membrane protein consisting of a heterodimer—one alpha and one beta chain, which participates in cell adhesion and cell surface-mediated signalling. The I-domain containing alpha 10 combines with integrin beta-1 chain to form a collagen type-II-binding integrin expressed in cartilage.
References in periodicals archive ?
Changes of integrin alpha-11 and isoform-1 of multimerin-1 were validated with Western blotting.
Using PLLB treatment, we were able to identify some low abundance proteins and proteins that are seldom implicated in MM, such as integrin alpha-11 and isoform-1 of multimerin-1.
Two of the differentially expressed proteins were selected for immunodetection in undepleted plasma using specific antibodies to integrin alpha-11 and isoform-1 of multimerin-1 and the differential serum levels were confirmed by Western blotting analysis [Figure 3].
We also found two novel proteins, integrin alpha-11 subunit and isoform-1 of multimerin-1 integrin alpha-11 was found to be overexpressed in nonsmall cell lung carcinoma (NSCLC) and in esophageal squamous cell carcinoma.