insulinoma

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insulinoma

 [in″su-lin-o´mah]
a tumor of the beta cells of the islets of Langerhans; although usually benign, it is one of the chief causes of hypoglycemia.

in·su·li·no·ma

(in'sŭ-li-nō'mă),
An islet cell adenoma that secretes insulin.

insulinoma

/in·su·li·no·ma/ (in″sdbobr-lin-o´mah) an islet cell tumor of the beta cells, usually benign, that secretes insulin and is one of the chief causes of hypoglycemia.

insulinoma

[in′səlinō′mə] pl. insulinomas, insulinomata
Etymology: L, insula + Gk, oma, tumor
a tumor, usually benign, of the insulin-secreting cells of the islets of Langerhans. Surgical resection of the tumor may be possible, thus limiting the development of hypoglycemia. Also called insuloma, islet cell adenoma. Compare islet cell tumor.
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Insulinoma

insulinoma

A well-differentiated pancreatic endocrine neoplasm associated with Whipple's triad:
(1) Symptoms and signs of hypoglycaemia;
(2) Concomitant plasma glucose level of 45 mg/dL or less; and
(3) Symptoms reverse with the administration of glucose. Amyloid is often found in insulinomas.

Prognosis
Insulinomas, especially if small, have an excellent prognosis.

insulinoma

Insuloma Oncology A pancreatic islet cell tumor, which is characterized by overproduction of insulin, resulting in hypoglycemia of sufficient severity to trigger a coma; insulinomas are typical of MEN I. See MEN I.

in·su·li·no·ma

(in'sŭ-li-nō'mă)
An islet cell adenoma that secretes insulin.
Synonym(s): insuloma.

insulinoma

A rare tumour of the INSULIN -producing cells of the PANCREAS. Insulinomas can produce large quantities of insulin and lead to the dangerous condition of HYPOGLYCAEMIA.

Insulinoma

Tumor that arises from the insulin-producing cells in the pancreas.

insulinoma

a tumor of the beta cells of the islets of Langerhans; although usually benign, it is one of the chief causes of hypoglycemia.
References in periodicals archive ?
Insulinomas are rare pancreatic neuroendocrine tumors, but they should always be considered in the differential diagnosis of any patient presenting with frequent hypoglycemic symptoms.
Mas del 99% de los insulinomas se originan en pancreas, con casos raros reportados en forma ectopica al tejido pancreatico.
Caspase-3 gene silencing for inhibiting apoptosis in insulinoma cells and human islets.
El 43% de insulinomas esta localizado en la cabeza y cuello del pancreas, el 30,9% en la cola y 25,3% en el cuerpo.
The nodule was determined to be an insulinoma on histological analysis.
However, since peripheral blood levels of CgA are not routinely tested in Chinese patients with the disease, the research aimed to evaluate the diagnostic value of CgA in Chinese patients with PNETs, especially in those with insulinomas.
2) Insulinoma is the common functional islet cell tumor and is usually single and intrapancreatic in location.
Low glucose levels (hypoglycemia) are seen with adrenal insufficiency, alcohol intake, extensive liver disease, hypopituitarism, hypothyroidism, insulin overdose, starvation, insulinomas (insulin-producing pancreatic tumors), and drugs--acetaminophen and anabolic steroids.
Notably, loss of heterozygosity of the same 11p15 region has been found in some insulinomas (19).
Dogs with insulinomas typically have abnormally low ([less than or equal to] 60 mg/dL) fasting blood glucose.