insulinoma


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Related to insulinoma: hypoglycemia

insulinoma

 [in″su-lin-o´mah]
a tumor of the beta cells of the islets of Langerhans; although usually benign, it is one of the chief causes of hypoglycemia.

in·su·li·no·ma

(in'sŭ-li-nō'mă),
An islet cell adenoma that secretes insulin.

insulinoma

A well-differentiated pancreatic endocrine neoplasm associated with Whipple's triad:
(1) Symptoms and signs of hypoglycaemia;
(2) Concomitant plasma glucose level of 45 mg/dL or less; and
(3) Symptoms reverse with the administration of glucose. Amyloid is often found in insulinomas.

Prognosis
Insulinomas, especially if small, have an excellent prognosis.

insulinoma

Insuloma Oncology A pancreatic islet cell tumor, which is characterized by overproduction of insulin, resulting in hypoglycemia of sufficient severity to trigger a coma; insulinomas are typical of MEN I. See MEN I.

in·su·li·no·ma

(in'sŭ-li-nō'mă)
An islet cell adenoma that secretes insulin.
Synonym(s): insuloma.

insulinoma

A rare tumour of the INSULIN -producing cells of the PANCREAS. Insulinomas can produce large quantities of insulin and lead to the dangerous condition of HYPOGLYCAEMIA.

Insulinoma

Tumor that arises from the insulin-producing cells in the pancreas.
References in periodicals archive ?
The patient was referred to our clinic with the prediagnosis of insulinoma after they measured fingertip blood glucose 26 mg/dL in the emergency service when she applied with neuroglycopenic symptoms.
Other treatment options, including arterial chemo-embolization, radiofrequency ablation, radionuclide therapy, and liver transplantation, can be used for curative purposes when liver metastases are unresectable; the morbidity and mortality in patients with insulinoma are predominantly the result of the persistent hypoglycemia rather than wide-spread dissemination of the tumor (7).
Prevalences are given as n (%) ZnT8A+ ZnT8A- p value Total 49 (58.2) 35 (41.6) - tTG IgA+ 4 (8.2) 4 (11.4) 0.07 Anti-TPO and/or 5 (10.2) 7 (20.0) 0.21 anti-TG+ GADA+ 27 (60.0) 15 (42.9) 0.27 IA-2A+ 38 (77.6) 19 (54.3) 0.02 IA+ 0 (00.0) 1 (2.8) - Other autoantibodies 7 (15.6) 8 (22.9) 0.007 ZnT8A+: zinc transporter 8 protein positive, znT8A-: Zinc transporter 8 protein negative, tTG: anti-tissue transglutaminase, IgA: immunoglobulin A, TPO: thyroid peroxidase, TG: thyroglobulin, GADA: glutamic acid decarboxylase antibodies, IA: insulinoma antigen, IA-2A: insulinoma antigen-2 antibody
Kinoshita and Kusamori reported that pseudoislet formation minimally improved glucose-responsive insulin secretion using mouse insulinoma MIN6 and NIT cells [25, 26].
From her family history and further investigation, she was diagnosed as having insulinoma and hyperparathyroidism in MEN-1.
Palmer, "Hemoglobin regulates the metabolic and synthetic function of rat insulinoma cells cultured in a hollow fiber bioreactor," Biotechnology and Bioengineering, vol.
Tumour Age to Biochemical test Imaging test begin(y) annually (Time interval) Parathyroid 8 Calcium, PTH None Pancreas 20 Gastrin None Gastrinoma Insulinoma 5 Fasting glucose, None Insulin Other <10 Chromogranin-A, MRI, CT or pancreatic NET PP, glucagon, VIP endoscopic US Pituitary 5 Prolactin, IGF-1 MRI (every 3 y) Adrenal 19 None unless >1cm lesion or MRI or CT symptoms Thymic and 15 None CT or MRI(1-2y) bronchial carcinoid
[30] have described five patients with insulinoma who received EUS-guided ethanol ablation, and there were no complications observed during or after the EUS-guided procedure.
An insulinoma is a tumour of which organ of the body?
Uros Milosevic, author of the article "CENTRAL PANCREATECTOMY IN SURGICAL TREATMENT OF PANCREATIC INSULINOMA", published in the journal Medical Review, 3-4/2017, pages 111-114, we hereby provide the correct email address of the author: uros.milosevic@mf.uns.ac.rs.
Included patients with known diabetes, chronic renal failure, liver cell diseases, endocrine disorders such as insulinoma, postpancreatectomy, patients on drugs such as somatostatin, beta blockers, diazoxide, thiazide diuretics, phenytoin, alloxan, and steroids pregnant women, post-menopausal women, people with fever, people who had edema, patient with osteoporosis with very low bone density, body builders or professional athletes, patients undergoing dialysis, and persons with pacemaker were excluded from the study.