IGFBP2

(redirected from insulin-like growth factor binding protein 2)

IGFBP2

A gene on chromosome 2q33-q34 that encodes a member of the insulin-like growth factor binding protein (IGFBP) family that binds insulin-like growth I and II and circulates in the plasma. IGFBP2 binding prolongs the half-life of the IGFs, alters their interaction with cell surface receptors, and inhibits IGF-mediated growth and development.
References in periodicals archive ?
Kim, "The role of insulin-like growth factor binding protein 2 (IGFBP2) in the regulation of corneal fibroblast differentiation," Investigative Ophthalmology & Visual Science, vol.
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