insulin receptor substrate-2


Also found in: Acronyms.

insulin receptor substrate-2 (IRS-2),

intracellular molecules that are activated by insulin and mediate many of its effects.
References in periodicals archive ?
Eldar-Finkelman, "Sequential phosphorylation of insulin receptor substrate-2 by glycogen synthase kinase-3 and c-Jun NH2-terminal kinase plays a role in hepatic insulin signaling," American Journal of Physiology: Endocrinology and Metabolism, vol.
Tyrosine phosphorylation and protein expression of insulin receptor substrate-2 in the adipose tissue from patients with polycystic ovary syndrome.
Growth hormone, interferon-gamma, and leukemia inhibitory factor utilize insulin receptor substrate-2 in intracellular signaling.
Obesity in insulin receptor substrate-2 deficient mice: disrupted control of arcuate nucleus neuropeptides.

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