insulin autoimmune syndrome

insulin autoimmune syndrome

A rare cause of hypoglycemia, in which low levels of blood glucose are found in the setting of high levels of immunoreactive insulin, low levels of free insulin, and the presence of anti-insulin antibodies in the blood. The disease is often associated with other autoimmune disorders and frequently follows the treatment for those disorders (e.g., Graves' disease) with medications (such as methimazole) that contain sulfhydryl moieties.
References in periodicals archive ?
Autoimmune hypoglycemia, also called insulin autoimmune syndrome (IAS), wasfirst reported by Hirata and Ishizu[sup][1] in 1972 in Japan.
Three cases of hyperthyroidism combined insulin autoimmune syndrome (in Chinese).
Worldwide differences in the incidence of insulin autoimmune syndrome (Hirata disease) with respect to the evolution of HLA-DR4 alleles.