Insertional mutagenesis | definition of insertional mutagenesis by Medical dictionary
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mutation caused by insertion of new genetic material into a normal gene, particularly of retroviruses into chromosomal DNA.
in·ser·tion·al mu·ta·gen·e·sis (in-sĕr'shŭn-ăl myū'tă-jen'ĕ-sis)
Mutation caused by insertion of new genetic material into a normal gene, particularly of retroviruses into chromosomal DNA.
References in periodicals archive
Agrobacterium- mediated transformation of Fusarium oxysporrum: an efficient tool for insertional mutagenesis
and gene transfer.
The DNA sequence analysis showed point mutation in 2 cases, insertional mutagenesis
in 4 cases.
This would simplify selection during breeding, avoid problems caused by insertional mutagenesis
, and allow rapid transfer of multiple transgenes to elite lines.
by Replication-Deficient Retroviral Vectors Encoding the Large T Oncogene by Zhixiong Li and Olga S.