insertional mutagenesis


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in·ser·tion·al mu·ta·gen·e·sis

mutation caused by insertion of new genetic material into a normal gene, particularly of retroviruses into chromosomal DNA.

in·ser·tion·al mu·ta·gen·e·sis

(in-sĕr'shŭn-ăl myū'tă-jen'ĕ-sis)
Mutation caused by insertion of new genetic material into a normal gene, particularly of retroviruses into chromosomal DNA.
References in periodicals archive ?
T-DNA insertional mutagenesis and microarray expression profiling are two powerful technologies for functional genomics research.
Agrobacterium- mediated transformation of Fusarium oxysporrum: an efficient tool for insertional mutagenesis and gene transfer.
Agrobacterium tumefaciens- mediated transformation for random insertional mutagenesis in Colletotrichum lagenarium.
Kang, "Agrobacterium-mediated transformation of Fusarium oxysporum: an efficient tool for insertional mutagenesis and gene transfer," Phytopathology, vol.
Han, "Agrobacterium tumefaciens-mediated transformation as a tool for insertional mutagenesis in medicinal fungus Cordyceps militarist Fungal Biology, vol.
Marmeisse, "Agrobacterium tumefaciens-mediated transformation as a tool for insertional mutagenesis in the symbiotic ectomycorrhizal fungus Hebeloma cylindrosporum," FEMS Microbiology Letters, vol.
This would simplify selection during breeding, avoid problems caused by insertional mutagenesis, and allow rapid transfer of multiple transgenes to elite lines.
The insertional mutagenesis model (Montgomery et al., 1987) would not predict differential transposable element accumulation, as there is no a priori reason to expect differences in the densities of functional genes within the euchromatic portions of larger chromosomes compared with smaller chromosomes in the same genome.