insertion sequence


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Related to insertion sequence: Inverted repeat, transposase

in·ser·tion se·quence

discrete DNA sequences of nucleotides that are repeated at various sites on bacterial chromosomes, certain plasmids, and bacteriophages and that can move from one site to another on the chromosome, to another plasmid in the same bacterium, or to a bacteriophage.

insertion sequence (IS)

a type of TRANSPOSABLE GENETIC ELEMENT that codes for its own transposition but which apparently carries no other genetic information. Generally it is several hundred base pairs in length. It is capable of causing MUTATION when it inserts into a GENE. Insertion sequences may exist as independent entities or may form the terminal parts of certain TRANSPOSONS.
References in periodicals archive ?
CTX-M-14] and insertion sequences ISEcp1 and IS903 as described (24-26).
CTX-M-14] gene is found between insertion sequences ISEcpl and IS903 as described (31).
For Tn4401, three descriptions have been published in which different insertion sequences were present upstream of [bla.
Also overrepresented was the deletion of the 52 pseudogenes that contain frame shift mutations and premature stop codons or that are disrupted by an insertion sequence.
Microarray data that indicated the presence of a deletion were verified by PCR analysis, which used primer pairs that spanned the insertion sequences of the respective plasmids, the flanking regions, or both.
The presence of an insertion sequence in the human LPAI isolate likely signifies that the virus in poultry mutated from HPAI to LPAI, and both were circulating among the birds on that source farm, the latter undetected.
A 3,000-bp insert from one strain was amplified and sequenced and found to comprise GBSi1, interrupted by an IS3-like insertion sequence identical to sequences found in both the genome MI strain of S.
Development of resistance during antimicrobial therapy caused by insertion sequence interruption of porin genes.
The study isolates were screened for various MGEs including insertion sequences (ISEcp1, IS26 and ISCR1) and Sul-1-type class1 integrons.
CTX-M] genes with insertion sequences like ISEcp1B might have contributed to the enhanced expression and mobilization of [bla.