inotropic agents

in·o·tro·pic a·gents

drugs that increase the force of contraction of cardiac muscle (for example, digitalis glycosides, amrinone, and epinephrine).

inotropic agents

Generally, any measure used to change the force of a muscle. In practice the term is used for drugs that increase the force of contraction of the heart and whose use is usually limited to cases of low-output HEART FAILURE. They include ADRENALINE and NORADRENALINE, isoprenaline, PHOSPHODIESTERASE INHIBITORS, DIGITALIS, DOPAMINE derivatives, dopexamine (Dopacard) and dobutamine (Dobutrex, Posiject). Their use calls for great skill and knowledge and is generally confined to cardiologists. From the Greek inos , a muscle and tropos , a turning.

in·o·tro·pic a·gents

(inō-trōpik ājĕnts)
Drugs that increase force of contraction cardiac muscle.
References in periodicals archive ?
Patient's capillary withdrawal time was prolonged (>5 sec) and were given inotropic agents, vasopressor support and saline challange twice a day (20 cc/kg) Her blood gases were; pH 6,56, pCO2: 104 mmHg, HCO3:9,2 mmol/L, Be:-31,6, lactat: 16,32 mmol/L at her admission.
The control group was given continuous low flow oxygen inhalation and inotropic agents, and their cardiac stress was also reduced.
Suggested escalating levels of treatment include no treatment for an abnormality on radiography alone; nasal supplemental oxygen for mild hypoxemia; continuous positive airway pressure through face mask for moderate hypoxemia[9] and intubation, mechanical ventilation, and positive end-expiratory pressure for severe hypoxemia; and volume replacement and inotropic agents for hypotension with low cardiac output.
Pimobendan is a phosphodiesterase III inhibitor and calcium channel sensitizer causing a inodilating effect, at reduced myocardial oxygen consumption energy expenditure when compared to other positive inotropic agents as indicated by Fuentes, 2004 and Atkinson et al.
Inotropic agents and broad-spectrum antibiotics were administered under the situation of severe sepsis.
While being on mechanical ventilation, he was given antibiotics, anticonvulsants, inotropic agents, oxygen supplementation, albumin infusion and other supportive management.
Temporary therapeutic measures include rapid fluid infusion, administration of positive inotropic agents, and pericardiocentesis.
New positive inotropic agents with higher safety margins and stronger effects on cardiac contractility have been introduced in human and veterinary cardiology during the last 20 years (3) and their use must be explored in the avian patient.
10] Acute Physiology and Chronic Health Evaluation (APACHE) II scores, [11] the presence of bowel sounds and co-administration of sedatives and inotropic agents were documented on enrolment.
The study retrospectively reviewed the medical records of 56 consecutive patients who presented to Tabba Heart Institute, Karachi, from June 2009 to June 2011 with STEMI (defined as electrocardiographic evidence of ST segment elevation of Greater than 1mm in Greater than 2 contiguous leads or new left bundle branch block) who developed cardiogenic shock (defined as presence of systolic blood pressure Less than 90mmHg or need of parenteral inotropic agents with evidence of systemic hypoperfusion like cold clammy skin, cerebral obtundation) within 36 hours of the onset of STEMI, and underwent PPCI within 18 hours of the onset of the shock.