inotropic agents

in·o·tro·pic a·gents

drugs that increase the force of contraction of cardiac muscle (for example, digitalis glycosides, amrinone, and epinephrine).

inotropic agents

Generally, any measure used to change the force of a muscle. In practice the term is used for drugs that increase the force of contraction of the heart and whose use is usually limited to cases of low-output HEART FAILURE. They include ADRENALINE and NORADRENALINE, isoprenaline, PHOSPHODIESTERASE INHIBITORS, DIGITALIS, DOPAMINE derivatives, dopexamine (Dopacard) and dobutamine (Dobutrex, Posiject). Their use calls for great skill and knowledge and is generally confined to cardiologists. From the Greek inos , a muscle and tropos , a turning.

in·o·tro·pic a·gents

(inō-trōpik ājĕnts)
Drugs that increase force of contraction cardiac muscle.
References in periodicals archive ?
Following the cardiopulmonary bypass, she had no need for inotropic agents. She was able to be extubated 24 hours after the operation.
Classes of drugs used in the management of acute heart failure include angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers, beta blockers, digoxin, diuretics, aldosterone antagonists, nitrates, inotropic agents, and anticoagulants.
Despite treatment with a mechanical ventilation, ECMO, inotropic agents, and oseltamivir, she died of ARDS and multiorgan failure after a 5-day stay in the ICU.
Of these, 2 had myocardial dysfunction and required multiple inotropic agents and renal replacement therapy.
This was likely the result of hyperdynamic ventricular contractility and stroke volume due to inotropic agents and severe aortic insufficiency, respectively.
Specifically, immediate and intensive treatment with colloidal fluid resuscitation, inotropic agents, adequate alimental support, and mechanical ventilation is indispensable for a favorable outcome, if needed [8].
He died nine hours after the admission to the hospital despite aggressive respiratory and circulatory support including intubation and mechanical ventilation, administration of inotropic agents and antibiotics.
Patient's capillary withdrawal time was prolonged (>5 sec) and were given inotropic agents, vasopressor support and saline challange twice a day (20 cc/kg) Her blood gases were; pH 6,56, pCO2: 104 mmHg, HCO3:9,2 mmol/L, Be:-31,6, lactat: 16,32 mmol/L at her admission.
Throughout HDF, the patient continued to be hypotensive and bradycardic necessitating an increased dose of inotropic agents. Metabolic acidosis was also persistent requiring repeated sodium bicarbonate administration.
The control group was given continuous low flow oxygen inhalation and inotropic agents, and their cardiac stress was also reduced.