Evidence for dual coupling of the murine luteinizing hormone receptor to adenylyl cyclase and phosphor inositide
breakdown and [Ca2.sup.+] mobilization.
These phosphorylated tyrosines serve as anchors for binding and activating downstream signaling elements such as phospholipase C (PLC), Shc, SNT and phosphatidyl inositide
Oh, "The inositide
signaling pathway as a target for treating gastric cancer and colorectal cancer," Frontiers in Physiology, vol.
By comparison, I[P.sub.3] is produced by the direct action of PLC on phosphatidyl 4,5-bisphosphate inositide