inosine


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Related to inosine: inosine pranobex

inosine

 (I) [in´o-sēn]
a purine nucleoside containing the base hypoxanthine and the sugar ribose, which occurs in transfer RNAs.
inosine monophosphate (IMP) a nucleotide produced by removal of the amine group from adenosine monophosphate in metabolism of purine nucleotides.

in·o·sine (I, Ino),

(in'ō-sēn),
9-β-d-Ribosylhypoxanthine; a nucleoside formed by the deamination of adenosine.
Synonym(s): hypoxanthinosine

inosine

/in·o·sine/ (I) (in´o-sēn) a purine nucleoside containing the base hypoxanthine and the sugar ribose, which occurs in transfer RNAs and as an intermediate in the degradation of purines and purine nucleosides to uric acid and in pathways of purine salvage.
inosine monophosphate  (IMP) a nucleotide produced by the deamination of adenosine monophosphate (AMP); it is the precursor of AMP and GMP in purine biosynthesis and an intermediate in purine salvage and in purine degradation.

inosine

(ĭn′ə-sēn′, -sĭn, ī′nə-)
n.
A nucleoside that is involved in purine metabolism, as a precursor and a metabolite of adenosine.

inosine

[in′əsēn, -sīn]
a nucleoside derived from animal tissue, especially intestines, originally used in food processing and flavoring. It has been used in the treatment of cardiac disorders and is now under investigation in studies of cancer and virus chemotherapy. See also inosiplex.

in·o·sine

(I, Ino) (in'ō-sēn)
A nucleoside formed by the deamination of adenosine.

inosine (I)

a NUCLEOSIDE found in some ANTICODONS of TRANSFER RNA. Inosine is ribosylhypoxanthine, the base being hypoxanthine, a derivative of ADENINE. Inosine generally occurs in the first position of the anticodon of certain tRNA molecules where it can base pair with U, C or A of the CODON on mRNA.

inosine

a nucleic acid derivative found naturally in brewer's yeast and organ meats. Not essential in the diet since the body can synthesize it from amino acids and glucose. Metabolically, takes part in formation of adenine, a component of ATP. It has been suggested that inosine supplementation might enhance exercise performance by increasing ATP supply but research studies have found no improvements. See also ergogenic aids; appendix 4.4 .

inosine (īˑ·nō·sēn),

n a nucleoside and precursor to adenosine, important biochemical in energy production. It may be useful as an adjunct treatment for cardiovascular conditions and for Tourette's syndrome. High doses may increase the levels of uric acid in the blood.

inosine

a purine nucleoside containing the base hypoxanthine and the sugar ribose, which occurs in transfer RNAs.

inosine monophosphate (IMP)
a nucleotide produced by the deamination of adenosine monophosphate (AMP) in the metabolism of purine nucleotides.
inosine 5-monophosphate
the first fully formed purine nucleotide in the pathway of purine synethesis. Called also IMP or inosinic acid.
References in periodicals archive ?
Effects of different dry-aging methods on the inosine 5'-monophosphate (IMP) and free amino acid contents (mg/100 g) of sirloin from low-marbled Hanwoo cow meat after 28 days Items Control TD (1) SD (1) SDB (1) SEM (2) (1) IMP 153.
Immuomodulatory and neuroprotective effects of inosine.
It was probably due to administration of buffered phosphorus along with inosine and sodium pyruvate.
Other germination mutants, such as gerP (which lacked inosine receptors) and gerN (which lacked germinant-transfer proteins), were also deficient in pressure-induced germination.
In the study, Inosine was shown to stimulate nerve cells in undamaged parts of the brain to grow new connections into brain areas that had lost their normal connections as a result of a stroke; this "rewiring" partially compensated for the loss of the original connections, and resulted in significant improvement in several types of behavior compared to rats that did not receive Inosine.
The findings suggest that inosine could boost recovery in many of the 600,000 people in the United States each year who have a stroke.
I note Inosine, Seven Seas One-a-Day, Glucosamine, Ginseng, Echinacea, Ginkgo Biloba, St John's Wort and Bloflavonalds.
Section 4 - Thermally Generated Flavour includes Studies on Intermediates Generating the Flavour Compounds 2-Methyl-3-furanthiol, 2-Acetyl-2-thiazoline and Sotlon by Maillard-type Reactions; New Aspects of the Formation of 3(2H)-Furanones through the Maillard Reaction; Off-Flavour Formation in the Heat Sterilized Meat in Trays; Studies on the Aroma of Roasted Coffee; Comparison of Three Sugars and Inosine Monophosphate as Precursors of Meat Aroma; Olfactometric Study of Cooked Cured Ham; Comparison of Some Aroma Impact in Roasted Coffee and Coffee Surrogates; Influence of Blanching on Aroma Compounds in Leeks during Frozen Storage.
Newport manufactures and supplies immunomodulating drug inosine acedoben dimepranol (IAD), which is indicated for the treatment of a range of viral infections in many countries around the world and sold under the trademarks Isoprinosine[R], Imunovir[R], Viruxan[R], Virimun[R] and Delimmun[R].
The results showed that aspartate, betaine, choline, cysteine, ethanol, and threonine were increased over 2-fold in the muscle; propionate and trimethylamine were increased over 2-fold in the plasma; and alanine, glycerol, inosine, lactate, and pyruvate were increased over 2-fold and acetoacetate, arginine, citrulline, creatine, glutamine, glutarate, hippurate, lysine, methionine, phenylacetylglycine, taurine, trigonelline, trimethylamine, and trimethylamine N-oxide were decreased below 0.
Trek Therapeutics, a private, clinical stage public benefit business developing low-cost and accessible treatment regimens for chronic hepatitis C virus (HCV) infection, has made an announcement on its acquisition of the worldwide development and commercialization rights to treat infectious disease with lomibuvir (VX-222), a non-nucleoside inhibitor of the HCV NS5B polymerase and merimepodib (VX-497), an inhibitor of inosine monosphosphate dehydrogenase with broad-spectrum antiviral properties from Vertex Pharmaceuticals Incorporated.
A small study conducted by MGH researchers and other scientists suggests that Itrim the nutritional supplement inosine might benefit people with Parkinson's disease (PD).