Our patient, with a LVEF of 12% and LVDD of 49 mm --diagnosed by exclusion more than 15 days after the initial visit-required invasive ventilation, vasopressor, inotropic and inodilator
(levosimendan) support on two occasions.
Pimobendan, an inodilator
has been found to reduce morbidity in CHF (Fuentes, 2004).
5 [micro]g/kg/ minute) was instituted as an inodilator
to increase myocardial contractility and reduce ventricular afterload.
Abraham's presentation outlined how nitroxyl donors are both mechanistically and physiologically distinct from all previous inodilator
therapies utilized in the treatment of this syndrome, which currently accounts for more hospitalizations in the USA for patients over age 65 years than any other diagnosis.
In that study, we showed the novel inodilator
agent levosimendan improved LA performance in patients with severe HF receiving optimal conventional treatment.
Coronary vasorelaxant effect of levosimendan, a new inodilator
with calcium-sensitizing properties.
Comparison of the vasorelaxing effect of cromakalim and the new inodilator
, levosimendan, in human isolated portal vein.
Levosimendan, a new inodilator
used in the treatment of decompensated heart failure, has been reported to be effective in patients with high perioperative risks, with abnormal left ventricular function, and who face difficulties in weaning off cardiopulmonary bypass (3).
Levosimendan, a novel inodilator
, may represent a therapeutic option in those patients who require improved right ventricular performance and reduced pulmonary vascular tone.
Adrenaline acted as an inoconstrictor, dobutamine an inodilator
and milrinone predominantly a vasodilator.
Milrinone with its inodilator
properties is particularly useful in supporting right ventricular function while reducing pulmonary vascular resistance.
Papp, "Inotropes and inodilators
for acute heart failure: sarcomere active drugs in focus," Journal of Cardiovascular Pharmacology, vol.