innate immunity


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in·nate im·mu·ni·ty

resistance manifested by a species (or by races, families, and individuals in a species) that has not been immunized (sensitized, allergized) by previous infection or vaccination; much of it results from body mechanisms that are poorly understood but differ from those responsible for the altered reactivity associated with the specific nature of acquired immunity; in general, innate immunity is nonspecific and is not stimulated by specific antigens.
See also: self.

innate immunity

innate immunity

The nonspecific first line of defence against foreign pathogens that is an integral facet of the immune response, which is mediated by dendritic cells (DCs), natural killer (NK) cells, macrophages, neutrophils, basophils, eosinophils and mast cells. Macrophages and mast cells serve as sentinels stationed in tissues, which continuously monitor their microenvironment for signs of distress.

in·nate im·mu·ni·ty

(i-nāt' i-myū'ni-tē)
Resistance manifested by an organism that has not been sensitized by previous infection or vaccination; innate immunity is nonspecific and is not stimulated by specific antigens.
See also: self
Synonym(s): natural immunity, nonspecific immunity.

innate immunity,

n the ability of the body to protect itself against foreign organisms and toxins. The defense mechanisms of skin, white blood cells, macrophages, stomach acid, and chemicals in the bloodstream are all part of innate immunity.

in·nate im·mu·ni·ty

(i-nāt' i-myū'ni-tē)
Resistance manifested by an organism that has not been sensitized by previous infection or vaccination; nonspecific and is not stimulated by specific antigens.
Synonym(s): natural immunity, nonspecific immunity.
References in periodicals archive ?
Fortunately, two botanicals, Cistanche and Reishi can provide a powerful, natural means of boosting both adaptive and innate immunity.
Activation of the complement cascade during innate immunity is preceded by (i) synthesis of the acute phase reactant, mannanbinding lectin (MBL) by IL-6-activated hepatocytes; and (ii) histamine/ bradykinin-mediated contraction of vascular endothelial cells via interaction with types [H.
coli suggesting this measure of innate immunity may be an indicator of individual quality (Wilcoxen et al.
Activation of innate immunity, in turn, can contribute to exacerbations of reactive airways disease.
In section 4, the paper presents the biological bases for Innate Immune then introduces the concept of adding innate immunity to membrane computing and demonstrates how it can be used to attack NP complete problems in linear time less than time taken by a P system without protection of immunity.
Ficolins are pattern-recognition lectins involved in the lectin-complement pathway; they play an important role in innate immunity (6).
Professor Anthony Segal, of University College London, who led the research, reported in a medical journal: "Our investigations identified defective innate immunity in Crohn's disease.
ANA975, an organ prodrug of Anadys' small molecule compound isatoribine, belongs to a new class of drugs being developed to regulate innate immunity by interacting with TLR7.
Based on current needs of pediatric medicine in China, the scholars' study will relate to one of eight areas including: human milk protective factors in relation to risk of viral infections, maintaining healthy skin in young children and prematurity and innate immunity.
The cell surface receptors of macrophages such as the TLR2 (toll-like receptor), TLR4, and FcaRI are important in innate immunity response, which includes inflammation and cytokine release in response to stimuli.
A component of innate immunity prevents bacterial biofilm development.
Priming of [gamma][delta]T cells (known to mediate innate immunity to microbes) with these antigens was found in vitro to evoke responses to bacteria.