The most frequent treatment-related adverse events reported were mild to moderate injection-site reactions
The most commonly reported adverse reactions were injection-site reactions
, fever, irritability, decreased appetite, and increased and/or decreased sleep.
Most common side effects: mild to moderate injection-site reactions
(itching, pain, swelling)
Those taking Betaseron experienced significantly more adverse injection-site reactions
than those using Avonex.
In addition, in terms of tolerability, injection-site reactions
occurred less frequently in those treated with abatacept compared with adalimumab (4.
Once-weekly dosing coupled with fewer injection-site reactions
(Durelli et al.
On January 31 the FDA announced that the FUZEON (enfuvirtide) package insert had been changed to include precautions to avoid injection-site reactions
, either using a needle, or the Biojector(r) 2000 needlefree injection system.
According to the FDA advisory, women may be at higher risk for injection-site reactions
due to typically higher fat thickness at the injection site.
There was no evidence of autoimmune reactions with prolonged use and the most common treatment-related adverse events were injection-site reactions
, which tended to diminish after the first year of treatment, the company said.
2008) Problems with injection-site reactions
: More patients who were nonadherent reported problems with injection-site reactions
(Devonshire et al.
Prevention and Management of Injection-Site Reactions
In studies of growth hormone-deficient children, injection-site reactions