initiation factor


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in·i·ti·a·tion fac·tor (IF),

one of several soluble proteins involved in the initiation of protein or RNA synthesis.

in·i·ti·a·tion fac·tor

(IF) (i-nish'ē-ā'shŭn fak'tŏr)
One of several soluble proteins involved in the initiation of protein or RNA synthesis.

initiation factor (IF)

one of a group of special proteins required for the initiation of protein synthesis; promoting the correct association of RIBOSOME and mRNA. see TRANSLATION.
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References in periodicals archive ?
Inhibition of translation initiation factors might be the potential therapeutic targets for HCV patients with hepatic iron overload.
Relationship between Hepatitis C Virus Infection and Iron Overload
The report reviews Eukaryotic Translation Initiation Factor 4E (eIF-4E) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
New Market Report: Eukaryotic Translation Initiation Factor 4E (eIF-4E) - Pipeline Review, H1 2016
A global inhibition of genes regulating eukaryotic initiation factors and ribosomal proteins has been observed (Table 3), implying that the overall protein synthesis was reduced due to sustained CPT-triggered UPR.
Cryptotanshinone deregulates unfolded protein response and eukaryotic initiation factor signaling in acute lymphoblastic leukemia cells
Relationship between eukaryotic translation initiation factor 4E and malignant angiogenesis in non-Hodgkin lymphoma.
Expression and phosphorylation of eukaryotic translation initiation factor 4E binding protein 1 in B-cell lymphomas and reactive lymphoid tissues
Archaeal translation initiation revisited: the initiation factor 2 and eukaryotic initiation factor 2B alpha-beta-delta subunit families.
Global analysis of microbial translation initiation regions
Effect of salubrinal on P-eukaryotic translation initiation factor 2a after brain death
Protective Effects of Salubrinal on Liver Injury in Rat Models of Brain Death
The heme-regulated eukaryotic initiation factor 2[alpha] kinase.
Elevated nitric oxide/peroxynitrite theory of multiple chemical sensitivity: central role of N-methyl-D-aspartate receptors in the sensitivity mechanism
Corixa Corporation (Seattle, WA; 206-754-5720), a research-based biotechnology company, announced that the United States Patent and Trademark Office has issued the company three patents granting composition and method claims covering Corixa's proprietary vaccine adjuvant protein known as Leishmania elongation Initiation Factor, or LeIF.
Corixa receives United States patents on vaccine adjuvant, LeIF
This study aimed to illustrate the negative role of eukaryotic initiation factor 6 (eIF6) in the process of human hypertrophic scar formation, and provide a possible indicator of hypertrophic scar treatment and a potential target molecule for hypertrophic scar.
Process of Hypertrophic Scar Formation: Expression of Eukaryotic Initiation Factor 6
Senesco is a cancer therapeutics company employing its strong proprietary platform in eukaryotic translation initiation Factor 5A (eIF5A) technology to regulate cell death and survival.
United States : Senesco Technologies announces positive results of combination of bortezomib and SNS01-T
They found that glucose deprivation caused an increase in BACE1 levels and led to the phosphorylation of the stress-inducible translation initiation factor, eIF2.
Mechanism linked to initiation of plaques in Alzheimer's identified
A sensitive immunoblotting method for measuring protein synthesis initiation factor levels in lysates of Escherichia coli.
Developmental increases in rat hepatic microsomal UDP-glucuronosyltransferase activities toward xenoestrogens and decreases during pregnancy. (Articles)

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