Inhibition of translation initiation factors
might be the potential therapeutic targets for HCV patients with hepatic iron overload.
The report reviews Eukaryotic Translation Initiation Factor
4E (eIF-4E) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
A global inhibition of genes regulating eukaryotic initiation factors
and ribosomal proteins has been observed (Table 3), implying that the overall protein synthesis was reduced due to sustained CPT-triggered UPR.
Relationship between eukaryotic translation initiation factor
4E and malignant angiogenesis in non-Hodgkin lymphoma.
Archaeal translation initiation revisited: the initiation factor
2 and eukaryotic initiation factor
2B alpha-beta-delta subunit families.
Effect of salubrinal on P-eukaryotic translation initiation factor
2a after brain death
The heme-regulated eukaryotic initiation factor
Corixa Corporation (Seattle, WA; 206-754-5720), a research-based biotechnology company, announced that the United States Patent and Trademark Office has issued the company three patents granting composition and method claims covering Corixa's proprietary vaccine adjuvant protein known as Leishmania elongation Initiation Factor
, or LeIF.
This study aimed to illustrate the negative role of eukaryotic initiation factor
6 (eIF6) in the process of human hypertrophic scar formation, and provide a possible indicator of hypertrophic scar treatment and a potential target molecule for hypertrophic scar.
Senesco is a cancer therapeutics company employing its strong proprietary platform in eukaryotic translation initiation Factor
5A (eIF5A) technology to regulate cell death and survival.
They found that glucose deprivation caused an increase in BACE1 levels and led to the phosphorylation of the stress-inducible translation initiation factor
A sensitive immunoblotting method for measuring protein synthesis initiation factor
levels in lysates of Escherichia coli.