inhibitory concentration


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inhibitory concentration

Abbreviation: IC
The concentration of a medication in the blood that will inhibit the replication of a specified percentage of microorganisms. The abbreviation IC is often followed by a number, e.g., 50 or 90. The IC50 of a drug to treat acquired immunodeficiency syndrome is the drug concentration that will inhibit replication of 50% of all HIV virions, and IC90 is the concentration that will inhibit 90% of the virions.
See also: concentration
References in periodicals archive ?
The determination of the Minimum Inhibitory Concentrations of the essential oils was performed using the Broth Microdilution technique, in accordance with the document M27-A4 by the Clinical and Laboratory Standards Institute (Clinical and Laboratory Standards Institute, 2013), adapted to phyto pharmaceuticals.
Table 8: Minimum inhibitory concentration (g mL-1) of flower extracts of C.
Determination of minimum inhibitory concentrations (MICs) of antimicrobial agents by agar dilution.
Data shows that compounds give similar activities with zone of inhibition and minimum inhibitory concentration. It will be interesting to probe in details the medicinal use of these compounds.
Darunavir concentrations in CSF exceed the median inhibitory concentration.
glaucescens leaf extract Table 2: Minimum Inhibitory Concentration (MIC) of the root and leaf extracts of T.
TABLE 1 Minimum inhibitory concentrations Bupivacaine Ropivacaine Levobupivacaine MIC (%) MIC (%) MIC (%) S.
The three most active oils were selected to determine the minimal inhibitory concentration (MIC) against the same Salmonella.
The data presented essentially point to an absence of in vitro resistance to dihydroartemisinin (dhART) in the panel of African isolates studied, with 1 of 397 isolates having an elevated 50% inhibitory concentration ([IC.sub.50]) for dhART.
Or perhaps in vitro or in vivo effectiveness doesn't quite match up because doses of antibiotics result in blood levels above the minimum inhibitory concentration for a substantial length of time, which is a predictor of eradication.
All but one of the ESBL-producing isolates were susceptible to the carbapenems imipenem and meropenem (minimum inhibitory concentration = 4 mcg/mL).

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