IAP

(redirected from inhibitor of apoptosis protein)
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IAP

IAP

1. Intermittent acute porphyria. See Acute intermittent porphyria.
2. Intraabdominal pressure.
3. Intraarterial pressure.

IAP

Abbreviation for intermittent acute porphyria.
References in periodicals archive ?
Abbreviations 7-AAD: 7-Aminoactinomycin D A5: Annexin-5 DIABLO: Direct IAP-Binding Protein with Low PI DMSO: Dimethylsulfoxide EGFR: Epidermal growth factor receptor ER: Estrogen receptor FDG: Fluorodeoxyglucose HER2: Human epidermal growth factor receptor 2 IAP: Inhibitor of apoptosis proteins IV: Intravenous NIH: National Institute PET: Positron emission tomography PR: Progesterone receptor SMAC: Second Mitochondria-derived Activator of Caspases SPECT: Single-photon emission tomography SUV: Standardized uptake values TGF-[beta]: Transforming growth factor-[beta] TNBC: Triple-negative breast cancer WHO: World Health Organization.
Zou et al., "Physiologically based pharmacokinetic and pharmacodynamic modeling of an antagonist (SM-406/AT-406) of multiple inhibitor of apoptosis proteins (IAPs) in a mouse xenograft model of human breast cancer," Biopharmaceutics & Drug Disposition, vol.
Afterwards, cells were lysed and whole proteins lysates were analysed by Western blot for altered expression of X-linked inhibitor of apoptosis protein (XIAP), baculoviral IAP repeat containing 5 (BIRC5), myeloid cell leukemia 1 (MCL1), B-cell lymphoma 2 (BCL2), and BCL2 like 1 (BCL2L1).
The inhibitor of apoptosis protein family and its antagonists in acute leukemias.
Antibody response to the tumor-associated inhibitor of apoptosis protein survivin in cancer patients.
Scott, "Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family," EMBO Reports, vol.
Debiopharm has entered into a collaboration with Merck KGaA and Pfizer to evaluate Debio 1143, an oral, small molecule inhibitor of IAPs (Inhibitor of Apoptosis Proteins), in combination with avelumab, an investigational fully human anti-PD-L1 IgG1 monoclonal antibody, in advanced or metastatic Non-Small Cell Lung Cancer (NSCLC).
Inhibitor of apoptosis proteins: translating basic knowledge into clinical practice.
Survivin is a new human gene encoding a structurally unique inhibitor of apoptosis proteins (IAP), apoptosis inhibitor, and plays an important role in the hyperplastic growth of tissues and tumors.
Table 1 List of various pro-apoptotic and anti-apoptotic factors involved in the sepsis Pro-apoptotic factors Anti-apoptotic factors BAX Bcl-2 Bcl-xs Bcl-xl, Bcl-Al BIM, PUMA, NOXA Inhibitor of apoptosis proteins FAS ligand Mcl-1 Tumour necrosis factor- a Ras factor- a BID, BAK Apoptosis-inducing factor p53 BAX=Bcl-2-associated X protein, Bcl=B cell lymphoma, BIM=Bcl-2-interacting moderator of cell death, PUMA=p53- upregulated modulator of apoptosis, NOXA=phorbol-12 myristate-l-acetate-induced protein, FAS=cell surface Fas receptor also known as CD95L, Mcl=M cell lymphoma, Ras=rat sarcoma, BID=BH3 interacting death domain, BAK=Bcl-2 homologous antagonist killer.
ARTS interferes with molecules called inhibitor of apoptosis proteins (IAPs), which prevent cells from killing themselves.
TL32711 is a synthetic, small molecule peptidomimetic of SMAC (an endogenous regulator of apoptotic cell death) that selectively antagonises multiple Inhibitor of Apoptosis Proteins (IAPs).

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