migration-inhibitory factor

(redirected from inhibition factor)

mi·gra·tion-in·hib·i·tor·y fac·tor (MIF),

a soluble, nondialyzable substance that is produced by sensitized lymphocytes (that is, lymphocytes from a sensitized animal) when exposed to the specific antigen, and that causes adherence and inhibition of migration of macrophages.
Synonym(s): inhibition factor
References in periodicals archive ?
For the inhibition factor, statistically significant difference was only found between the ADHD + learning difficulties group and pure ADHD group (A > B) (17.
The inhibition factor of the BRIEF also showed difference between the ADHD + learning difficulties group and pure ADHD group as the Stroop test whereas there was no significant difference between the diagnostic groups and the control group on the inhibition factor.
Finally, to tap the Inhibition factor, we chose the Stroop task, the Matching Familiar Figures Test-20 (MFFT20) and the Porteus maze.
Finally, the Inhibition factor may reflect the ability to inhibit and suppress irrelevant information to reach an objective.
Some of these defector molecules, migration inhibition factor (MIF) a lymphokine, inhibit the migration of macrophages in the same culture medium [11].
However, it showed high urinary iodide, suggesting the high iodine uptake could easily have upset the inhibition factor of the perchlorate.
When Mimivirus was used as an antigen in a migration inhibition factor assay, sero-conversion was found in patients with both community- and hospital-acquired pneumonia.
Although the typical morphologic traits of Mimivirus make its confusion with ameba organelles unlikely (Figure), positive serum samples tested on noninfected intact amebas suspended in PBS by using the same migration inhibition factor protocol did not show any reactivity.
Macrophage migration inhibition factor in the patient's blood in the presence of enalapril was positive.
17, 1996--Human Genome Sciences (NASDAQ: HGSI) announced today the issuance of US Patent 5,556,767 entitled Inflammatory Protein Gamma, renamed Macrophage Colony Inhibition Factor.
It is particularly suited for subsequent nucleic acid amplification because the extraction method yields ultra pure nucleic acid therewith overcoming the problem of inhibition factors.