inhaled insulin


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Related to inhaled insulin: Afrezza

inhaled insulin

Insulin given by inspiration, with the use of an inhaler. It may be composed of liquid droplets or a dry powder. One inhaled insulin product was removed from use in 2008 because of its adverse effects on the lungs.
See also: insulin
References in periodicals archive ?
Given the concerns about earlier inhaled insulin products, the potential impact of Afrezza on lung function has been investigated closely.
Heinemann et al., "Time-action profile of inhaled insulin in comparison with subcutaneously injected insulin lispro and regular human insulin," Diabetes Care, vol.
"We believe our inhaled insulin product is state-of-the-art and well-differentiated from powder based, non-electronic technology.
John Patton, who has over 25 years of experience developing inhaled insulin and other inhaled therapies.
Prandial inhaled insulin plus basal insulin glargine versus twice daily biaspart insulin for type 2 diabetes: a multicentre randomized trial.
Unfortunately, on June 27, 2014, the FDA approved another inhaled insulin drug.
Non-invasive inhalational insulin is an attractive alternative to parenteral insulin.2 Clinical trials have shown that glucose-lowering activity of inhaled insulin is comparable to subcutaneous insulin but with improved patient compliance.3 Its regular use is associated with fewer hypoglycaemic episodes and less risk for weight- gain as compared to subcutaneous insulin.4
Other companies have also tried to market inhaled insulin but have ended their development programs.
At a meeting of the FDA's Endocrinologic and Metabolic Drugs Advisory Committee, panelists voted 13-1 that the safety and efficacy data for the inhaled insulin, delivered with an inhaler, supported approval for treatment of adults with type 1 diabetes; they voted 14-0 that the data supported approval for treatment of adults with type 2 diabetes.
Pittas, "Meta-analysis: efficacy and safety of inhaled insulin therapy in adults with diabetes mellitus," Annals of Internal Medicine, vol.
The clinical effectiveness and cost-effectiveness of inhaled insulin in diabetes mellitus: a systematic review and economic evaluation.
The company said it was informed that the agency would not make a decision on whether to approve the product, a whistle-sized inhaled insulin device, by its Dec.