Brain imaging shows widespread white matter hyperintensities involving both supra and infratentorial
compartments that are considered highly specific for this type of leukoencephalopathy (Figure).
Definition of a positive MRI5 * One Gd-enhancing brain or cord lesion or 9 T2 hyperintense brain and/or cord lesions if there is no Gd-enhancing lesion * One or more brain infratentorial
or cord lesion * One or more juxtacortical lesion * Three or more periventricular lesions * A Gd-enhancing lesion detected in a scan done at least 3 months after onset of initial clinical event at a site different from the initial event or a new T2 lesion detected in a scan done at any time compared with a reference scan done at least 30 days after initial clinical event.
Whereas DNT is typically a supratentorial, multinodular, and intracortical tumor in children or young adults with seizures and no neurologic deficit, (24) rosetted glioneuronal tumor of the fourth ventricle is an infratentorial
, intraventricular mass lesion affecting a slightly older age group which presents with signs of ventricular obstruction and which may cause focal deficits.
To demonstrate dissemination in space, the new criteria require three of the following: at least one gadolinium-enhanced lesion or nine T2 lesions, at least one infratentorial
lesion, at least one juxtacortical lesion, or at least three periventricular lesions.
In this study, there were 4 cases of tumours, 2 of them were of infratentorial
origin--fourth ventricle masses causing dilatation of proximal ventricles showing variable/irregular contrast enhancement, one was dysembryoplastic neuroepithelial tumour and other was of hypothalamic hamartoma.
023) and cerebrovascular disease and infratentorial
involvement (OR = 10.
Debido a la rareza de esta lesion y sobre todo en region infratentorial
, se decide cruzar el estudio histopatologico en otra institucion hospitalaria de igual rango cientifico, donde se confirma el diagnostico de Gliosarcoma.
This scale is a scale which classifies HWMs regionally as frontal, parietooccipital, temporal, infratentorial
and basal ganglia hyperintensities.
Supratentorial astrocytomas are more likely to be high grade compared with their infratentorial
CMs, distributed between the brainstem and the cerebellum, account for approximately another 15%.
VHL commonly presents with multiple hemangioblastomas, usually these are infratentorial
affecting the cerebellum, brainstem, spinal cord and eye.
10) In the present case, the symptomatic infratentorial
lesion was not gadolinium-enhancing but DWI-positive during all three clinical exacerbations.