inflammatory fibroid polyp

inflammatory fibroid polyp (GI tract)

An intraluminal projection of mucosa formed from non-neoplastic stromal and epithelial elements admixed with inflammatory cells.

A non-neoplastic, reactive, recurrent, often bilateral “tumour” formed in response to infection, allergy, mucoviscidosis.

Allergy, vasomotor rhinitis, infection, aspirin, cystic fibrosis, secondary changes caused by infarction, infection, vascular proliferation.

Any of a number of often bizarre polyps and/or bridges of mucosa, which when single may mimic malignancy and when multiple mimic a polyposis syndrome; Ips may arise in a background of inflammatory bowel disease—Crohn’s disease, ulcerative colitis, amoebic colitis, bacterial dysentery, and chronic schistosomiasis—and are benign, nonspecific sequelae of inflammation of the intestinal mucosa.
Clinical findings
Ips are rarely symptomatic, but pain, obstruction and, if large, intussusception may occur.  

Inflammatory fibrous polyp stages
Ÿ Nodular—Immature fibroblasts, loose myxoid stroma.
Ÿ Fibrovascular—Concentric mature fibroblasts, endothelial proliferation, eosinophil infiltration.
ŸSclerotic/oedematous—Collagenisation or vascular compromise.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
The second group is non-mucosal intramural polyps, such as the gastrointestinal stromal tumor, leiomyoma, inflammatory fibroid polyp, fibroma and fibromyoma, lipoma, ectopic pancreas, neurogenic and vascular tumors, and neuroendocrine tumors (carcinoids).
These abnormal characteristics have been limited to use in pathogenesis and are currently now used as diagnostic characteristic adjuncts [2] The differential diagnosis for GISTs currently include intra-abdominal fibromatosis, inflammatory fibroid polyp, paragangliomas and metastatic malignant melanoma.
Inflammatory fibroid polyp (IFP) is a group of rare benign mesenchymal tumors throughout the gastrointestinal tract.
The morphological picture of a cellular and atypical spindle cell tumor raised the differentials of GIST, smooth muscle tumor, desmoid tumor, fibrosarcoma, and inflammatory fibroid polyp. The absence of a collagenous and myxoid stroma ruled out a desmoid tumor.
Nonneoplastic submucosal gastric lesions include inflammatory fibroid polyp. Inflammatory fibroid polyp exhibits a submucosal proliferation of bland spindle-shaped cells, prominent vessels, and inflammatory cells "typically" rich in eosinophils dispersed in a fibromyxoid stroma.
Inflammatory fibroid polyp (IFP) is an uncommon benign lesion of the gastrointestinal tract [4].
Various cases have been reported due to underlying adenoma, lipoma, primary malignant neoplasm, lymphoma, metastatic lesion, Meckel's diverticulum, Crohn's disease, adhesion, Peutz-Jeghers polyp, inflammatory fibroid polyp, enteric tube, or congenital band.
Vanek's tumor, or inflammatory fibroid polyp (IFP), is one of the least common benign small bowel tumors [1, 2].
However, the prominence of eosinophils and condensation of spindled cells around vessels may be helpful features that favor a diagnosis of an inflammatory fibroid polyp. (26)
(35) The differential diagnosis includes schwannoma, myxoma, inflammatory fibroid polyp, and GIST.
The inflammatory fibroid polyp (IFP) is a localized lesion of the gastrointestinal tract constituted by a proliferation of spindle, stellate, or epithelioid mesenchymal cells infiltrated by a variable number of inflammatory cells, including lymphocytes, eosinophils, and mast cells, with a vascularized stroma with collagen fibers.

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