inflammatory fibroid polyp
inflammatory fibroid polyp (GI tract)Colon
An intraluminal projection of mucosa formed from non-neoplastic stromal and epithelial elements admixed with inflammatory cells.
A non-neoplastic, reactive, recurrent, often bilateral “tumour” formed in response to infection, allergy, mucoviscidosis.
Allergy, vasomotor rhinitis, infection, aspirin, cystic fibrosis, secondary changes caused by infarction, infection, vascular proliferation.
Any of a number of often bizarre polyps and/or bridges of mucosa, which when single may mimic malignancy and when multiple mimic a polyposis syndrome; Ips may arise in a background of inflammatory bowel disease—Crohn’s disease, ulcerative colitis, amoebic colitis, bacterial dysentery, and chronic schistosomiasis—and are benign, nonspecific sequelae of inflammation of the intestinal mucosa.
Ips are rarely symptomatic, but pain, obstruction and, if large, intussusception may occur.
Inflammatory fibrous polyp stages
Nodular—Immature fibroblasts, loose myxoid stroma.
Fibrovascular—Concentric mature fibroblasts, endothelial proliferation, eosinophil infiltration.
Sclerotic/oedematous—Collagenisation or vascular compromise.