Congenital infantile fibrosarcoma (CIFS) is a rare tumour of childhood.
Treatment of infantile fibrosarcoma with chemotherapy and surgery: Results from the Dana-Faber Cancer Institute and Children's Hospital, Boston.
Rachel, who lived with parents Anamarie and Florin and brothers Timothy, six, and Luke, four, in Buckley, battled through bouts of gruelling chemotherapy and treatment after she was diagnosed with infantile fibrosarcoma
The lowest age in which tumour found was a 25 day old baby girl who was diagnosed of Infantile Fibrosarcoma
The nine-month-old was thought to have been the only child in Britain with infantile fibrosarcoma
when she was diagnosed at three weeks.
A biopsy of the mass revealed infantile fibrosarcoma
Recently, both cellular mesoblastic nephroma and infantile fibrosarcoma
were shown to carry the t(12;15)(p13;q25) translocation, resulting in an ETV6-NTRK3 gene fusion.
Congenital infantile fibrosarcoma
is a common tumour in the sacrococcygeal region of infants.
Rachel has battled through bouts of tough chemotherapy and treatment since she was diagnosed with infantile fibrosarcoma
, which has left her with a tumour on her left hip.
The differential diagnosis for infantile myofibromatosis includes other types of fibromatosis, congenital infantile fibrosarcoma
, infantile hemangiopericytoma, inflammatory myofibroblastic tumors, fibrohistiocytic tumors with a predominantly fibrous pattern, smooth muscle tumors such as leiomyomas and leiomyosarcomas, neurogenic tumors such as neurofibromas and low-grade malignant peripheral nerve sheath tumors, and nodular fasciitis.
Treatment of infantile fibrosarcoma
with chemotherapy and surgery: Results from the Dana-Farber Cancer Institute and Children's Hospital, Boston.
Microscopically, infantile fibromatosis must be differentiated from infantile myofibromatosis and infantile fibrosarcoma
because their histologic resemblance is close.