Rachel, who lived with parents Anamarie and Florin and brothers Timothy, six, and Luke, four, in Buckley, battled through bouts of gruelling chemotherapy and treatment after she was diagnosed with infantile fibrosarcoma
The nine-month-old was thought to have been the only child in Britain with infantile fibrosarcoma
when she was diagnosed at three weeks.
A biopsy of the mass revealed infantile fibrosarcoma (IF).
Infantile fibrosarcoma is a rare type of sarcoma arising from fibroblasts; it generally presents as a soft-tissue mass occurring in the head and neck, primarily in the first 5 years of life but more commonly before the age of 2 years.
Infantile fibrosarcoma and infantile fibromatosis diagnosis and treatment: Clinical presentation of three cases.
Primary congenital infantile fibrosarcoma of the heart: The first confirmed case.
Unusual presentation of congenital infantile fibrosarcoma in seven infants with molecular-genetic analysis.
Recently, both cellular mesoblastic nephroma and infantile fibrosarcoma
were shown to carry the t(12;15)(p13;q25) translocation, resulting in an ETV6-NTRK3 gene fusion.
Rachel has battled through bouts of tough chemotherapy and treatment since she was diagnosed with infantile fibrosarcoma
, which has left her with a tumour on her left hip.
Treatment of infantile fibrosarcoma
with chemotherapy and surgery: Results from the Dana-Farber Cancer Institute and Children's Hospital, Boston.
Microscopically, infantile fibromatosis must be differentiated from infantile myofibromatosis and infantile fibrosarcoma
because their histologic resemblance is close.