infantile acropustulosis

in·fan·tile ac·ro·pus·tu·lo·sis

a cyclically recurrent vesicopustular and crusting pruritic eruption, usually in black children, appearing soon after birth to 10 months; remission occurs at about 2 years of age.

in·fan·tile ac·ro·pus·tu·lo·sis

(in'făn-tīl ak'rō-pŭs'tyū-lō'sis)
A recurrent papulopustular and crusting pruritic eruption, usually in black children.

infantile acropustulosis

(ak″rō-pŭs″tyŭ-lō′sĭs) [ acro- + pustulosis]
Cyclical eruption of pustules on the soles and feet of infants 2 to 10 months of age. The pustules become vesicopapular, crust over, and heal in 7 to 10 days. A new crop appears in 2 to 3 weeks, and they also heal. Periodic outbreaks occur for about 2 years and then cease. The cause is unknown; only symptomatic therapy is required.
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Early reports suggested a predominance of African Americans for infantile acropustulosis.
No doubt that scabies is comparatively more common as compared to infantile acropustulosis but yet scabies must not be considered as an absolute diagnosis for a patient presenting with an itchy rash particularly on soles.
We report a similar rash in an infant who was repeatedly treated as scabies but in the end turned out to have an uncommon underlying diagnosis of Infantile Acropustulosis.
However, among pustular diseases, Infantile acropustulosis is not very common6.
The duration of persistence of infantile acropustulosis is about two years9,10.
Although infantile acropustulosis responds well to sulphones like dapsone12 but due to its potential side effects, the exact treatment still remains controversial13.
In case of infants and children conditions including infantile acropustulosis, syphilis, seborrheic dermatitis, linear IgA bullous dermatosis, herpes gestationis, folliculitis and vesicular pemphigoid may need to be considered in the differential diagnosis of scabies21,22.
Based on the history and examination, a clinical diagnosis of infantile acropustulosis was made.
The exact etiology of infantile acropustulosis is unknown11 however; a relationship of infantile acropustulosis with scabies has been reported in studies by Prendiville23 and Mancini24.
The clinical cases reported by Gupta25, Elpern26 and Bjonberg27 reveals that infantile acropustulosis occurred after preceding scabies.
In a case report published by Lee et al, a child developed infantile acropustulosis after her treatment for scabies3.
A case of infantile acropustulosis reported by Marcus in Germany resolved with the application of topical corticosteroids to the patient.

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